Search for dissertations about: "male reproductive tract"

Showing result 1 - 5 of 12 swedish dissertations containing the words male reproductive tract.

  2. 1. Male Subfertility and Prostate Cancer Risk: Epidemiological and Genetic Studies

    Author : Yasir Ruhayel; Malmö Molekylärgenetisk reproduktionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cytoplasmic and nuclear; Receptors; Prostatic neoplasms; genetic; Polymorphism; male; Infertility; Hypogonadism; Genetic association studies; Case–control studies; Androgens;

    Abstract : Androgen action plays a pivotal role in male reproductive tract physiology and pathology. The androgen receptor (AR) gene harbors two codon repeat tracts: the CAG and GGN repeats, encoding corresponding amino acid sequences of variable length; the polyglutamine and polyglycine stretches, respectively. READ MORE

  4. 2. CYSTATIN C AND NEUROENDOCRINE DIFFERENTIATION IN THE MALE REPRODUCTIVE SYSTEM AND IN PROSTATE CANCER

    Author : Thomas Jiborn; Malmö Urologisk cancerforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urology; androgen deprivation therapy; cysteine protease inhibitor; neuroendocrine differentiation; cysteine protease; male reproductive tract; prostate cancer; nefrologi; Urologi; nephrology;

    Abstract : Cystatins are endogenous protease inhibitors that regulate the proteolytic activities of family C1 (papain-like) cysteine proteases, such as human cathepsins B, H, K, L, and S. Cystatin C shows the fastest inhibition and the highest affinity of all cystatins towards lysosomal cysteine proteases in general and is widespread in human tissues and body fluids. READ MORE

  5. 3. Reproductive toxicology of endocrine disruptors : effects of cadmium, phthalates and phytoestrogens on testicular steroidogenesis

    Author : David Gunnarsson; Gunnar Selstam; Gunnar Nordberg; Per Leffler; Henrik Leffers; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Endocrine disruptors; reproductive toxicology; cadmium; phthalates; DEHP; MEHP; phytoestrogens; steroidogenesis; testosterone; Leydig cell; Molecular biology; Molekylärbiologi;

    Abstract : A number of investigations during the last two decades describe adverse trends in male reproductive health, which have been proposed to be caused by environmental factors with endocrine disrupting properties. In contrast to many other toxicants, endocrine disruptors often do not show linear dose-response relationships typical of those found in traditional toxicological studies. READ MORE

  6. 4. Nitric oxide, formation and effects in the urogenital tract

    Author : Ingrid Ehren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : urinary tract; male reproductive tract; nitric oxide; nitric oxide synthase; NADPH-diaphorase; smooth muscle; secretion; inflammation; sex hormones.STOCKHOLM 1996 ISB;

    Abstract : The aim of the thesis was to study the formation and effects of nitric oxide (NO) in the human urinary tract and in the male reproductive organs. In the human upper and lower urinary tract NO synthase activity was studied via the formation of radiolabeled L-citrulline from L-arginine. READ MORE

  7. 5. Structure, Evolution, and Expression of Proteins in the Male Reproductive Tract. Studies on Semenogelins, Beta-Microseminoprotein, and PC3-Secreted Microprotein

    Author : Camilla Valtonen-André; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PC3-secreted microprotein; Clinical chemistry; Klinisk kemi; Semenogelin; Beta-microseminoprotein;

    Abstract : Human semen has several important constituents, including the prostate secreted proteins beta-microseminoprotein (MSP), prostate-specific antigen (PSA) and prostatic acid phosphatase (PAP), and the seminal-vesicle-derived coagulum proteins semenogelin I (SEMG1) and semenogelin II (SEMG2). The research underlying this thesis explored the evolution, expression and structure of seminal plasma proteins to provide further knowledge in the area of reproduction, particularly regarding MSP and the semenogelins. READ MORE