Search for dissertations about: "malonyl-CoA"

Showing result 1 - 5 of 8 swedish dissertations containing the word malonyl-CoA.

  2. 1. Metabolite biosensors for cell factory development

    Author : Yasaman Dabirian; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; malonyl-CoA; metabolite-responsive transcription factor-based biosensors; Saccharomyces cerevisiae; alkanes; fatty acyl-CoA; synthetic biology;

    Abstract : Through synergy with natural sciences and engineering disciplines, biotechnology has become a broad, interdisciplinary, scientific field with many applications. One such application is the sustainable production of industrially relevant products using living systems such as microorganisms. READ MORE

  4. 2. Effects of prolactin on metabolism - changes induced by hyperprolactinemia

    Author : Louise Nilsson; Göteborgs universitet; []
    Keywords : prolactin; prolactin receptor; hyperprolactinemia; adipose tissue; lipoprotein lipase; malonyl-CoA; glucose transporter 4; retinol-binding protein 4; adiponectin; lipid oxidation;

    Abstract : High prolactin levels during breast-feeding, is recognized to influence metabolism in order to supply glucose and fat for milk production. Pathologic overproduction of prolactin, hyperprolactinemia, is a condition primarily associated with reproductive disorders; however, the metabolic impact of elevated prolactin indicates that these parameters might be considered in clinical management of the condition. READ MORE

  5. 3. Pathogenesis of type 2 diabetes with emphasis on the mechanism of insulin resistance

    Author : Jeanette Kuhl; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Acetyl CoA carboxylase; AMP-activated protein kinase; Glucose intolerance; Insulin secretion; Insulin sensitivity; Malonyl CoA; Malonyl CoA decarboxylase; Peroxisomal proliferator activated receptor ã co-activator 1 á; Type 2 diabetes heredity;

    Abstract : Type 2 diabetes is characterized by chronic hyperglycemia and develops slowly through stages of early impairments of glucose metabolism. The disease is often associated with obesity, physical inactivity, decreased insulin sensitivity and impaired insulin responsiveness. READ MORE

  6. 4. Metabolic engineering of S. cerevisiae for the production of flavonoids

    Author : Marta Tous Mohedano; Chalmers tekniska högskola; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; microbial cell factories; high-value products; sustainability; cinnamic acid; plant natural products; Genetic engineering; yeast;

    Abstract : The interest in the production of natural products such as flavonoids has been increasing during the last decade. Flavonoids have several attractive bioactivities including antitumoral, antioxidant or antimicrobial properties. To produce these high-value products, we usually recur to chemical synthesis or plant extraction. READ MORE

  7. 5. Improving flavonoid production in Saccharomyces cerevisiae using synthetic biology tools

    Author : Dany Liu; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; metabolic engineering; biosensors; in vivo directed evolution; enzyme scaffolding; yeast;

    Abstract : Flavonoids are plant secondary metabolites and represent one of the largest classes of natural products. Due to their health-beneficial properties, they have found potential applications in foods, beverages, cosmetics, and pharmaceuticals. Currently, their production is based on extraction from plant material. READ MORE