Search for dissertations about: "marine drugs"

Found 4 swedish dissertations containing the words marine drugs.

  2. 1. Drug-drug interactions : from knowledge base to clinical impact

    Author : Marine Andersson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Drug usage has increased steadily, and the more drugs used, the higher the risk for adverse effects or loss of effect due to drug-drug interactions. For drug prescribers it is difficult to know what drugs a patient is taking and whether they interact. READ MORE

  4. 2. Control of bioluminescence. Operating the light switch in photophores from marine animals

    Author : Jenny Krönström; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; bioluminescence; physiological control; nitric oxide; krill; fish;

    Abstract : Physiologically controlled photocytes, capable of producing bioluminescence, are a common feature in the ocean among animals ranging from cnidarians to fish. The aim of this thesis was to study and compare the nature of this control, in both distantly and closely related species from the groups Teleostei Crustacea, and Cnidaria. READ MORE

  5. 3. Drug discovery against leishmaniasis : Bio- and chemoinformatic guided strategies for target evaluation and hit identification

    Author : Elisabet Vikeved; UCM Alsmark; Christian Sköld; David Horn; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Leishmaniasis; Drug discovery; Lateral gene transfer; Comparative genomics; Virtual screening; Target fishing; Marine natural products;

    Abstract : Leishmaniasis is a neglected tropical disease mainly affecting poor people in developing countries. It is caused by infections of flagellated protozoa belonging to genus Leishmania. The few available drugs are associated with problems such as low effectiveness, severe side effects and resistance development. READ MORE

  6. 4. Protein Interaction Studies with Low Molecular Weight Ligands : Applications for Drug Discovery, Basic Research and Diagnostic Tool Design

    Author : Tony Christopeit; U.Helena Danielson; Danièle Altschuh; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : In this thesis, the interactions between different proteins and small ligands were characterized by surface plasmon resonance spectroscopy (SPR) and fluorescence resonance energy transfer (FRET) based assays.   For the C-reactive protein (CRP), a new type of artificial binder was identified which allows designing diagnostic assays superior to commonly used standard assays. READ MORE