Search for dissertations about: "marinobufagenin"

Found 2 swedish dissertations containing the word marinobufagenin.

  2. 1. Signaling to and from the sodium pump : effects of insulin and cardiotonic steroids

    Author : Olga Kotova; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Na ; K -ATPase; insulin; C-peptide; exercise; in vitro contraction; cardiotonic steroids; ouabain; marinobufagenin; ERK 1 2 MAP kinase; Src; p90 rsk; GSK3; signaling cascade; glycogen synthesis; human skeletal muscle cells; human renal tubular cells; rat skeletal muscle.;

    Abstract : Insulin and proinsulin-connecting peptide (C-peptide) stimulate Na+,K+-ATPase activity. The molecular mechanism by which insulin and C-peptide regulate the Na-pump in differentiated primary human skeletal muscle cells (HSMCs) and primary human renal tubular cells (HRTCs) was determined. READ MORE

  4. 2. Nephroprotective effect of the cardiotonic steroid ouabain

    Author : Ievgeniia Burlaka; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : It has been shown that Na,K-ATPase (NKA) is a signal transducer. Our group described the anti-apoptotic effect of ouabain to the signaling function of NKA. READ MORE