Advanced search

Showing result 1 - 5 of 122 swedish dissertations matching the above criteria.

2. 1. Mass Spectrometry of Biologically Active Small Molecules : Focusing on polyphenols, alkaloids and amino acids

   Author : Zdeněk Spáčil; Leopold L. Ilag; Frantisek Turecek; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; LC-MS; LDI; Mass spectrometry; HPLC; UHPLC; polyphenols; phenolic acids; BMAA; Separation methods; Separationsmetoder; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

   Abstract : The foci of this dissertation are on advanced liquid chromatography (LC) separation and mass spectrometry (MS) techniques for the analysis of small bioactive molecules. In addition to discussing general aspects of such techniques the results from analyses of polyphenols (PPs), alkaloids and amino acids published in five appended studies are presented and discussed. READ MORE

4. 2. Liquid Chromatography Coupled to Mass Spectrometry : Implementation of Chemometric Optimization and Selected Applications

   Author : My Moberg; Jonas Bergquist; Karin E. Markides; Dan Bylund; Douglas B. Kell; Uppsala universitet; []
   Keywords : Analytical chemistry; liquid chromatography; mass spectrometry; tandem mass spectrometry; electrospray ionization; inductively coupled plasma; chemometrics; optimization; multivariate data analysis; design of experiments; response surface model; siderophore; azathioprine; peptide; Analytisk kemi;

   Abstract : Liquid chromatography (LC) coupled to mass spectrometry (MS) offers highly selective and sensitive analysis of a wide variety of compounds. However, the use of hyphenated experimental set-ups implies that many parameters may have an effect on the studied response. READ MORE

5. 3. Damsel in distress – metabolomics as a novel tool to investigate the effects of wastewater exposure on damselfly larvae

   Author : Jana Späth; Malin L. Nording; Jerker Fick; Stina Jansson; Tuulia Hyötyläinen; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; biomarkers; ecotoxicology; invertebrates; GC-MS; LC-MS; LC-MS MS; metabolomics; micropollutants; pharmaceuticals; risk assessment; ekotoxikologi; Ecotoxicology; Analytical Chemistry; analytisk kemi;

   Abstract : Aquatic organisms, such as aquatic invertebrates, are exposed to anthropogenic pollutants through their environment. These pollutants, despite their low levels, can adversely affect exposed individuals or even entire ecosystems, especially when present in complex mixtures. READ MORE

6. 4. Amino acids with relevance to health, climate and the environment : Development of mass spectrometric methods

   Author : Javier Zurita; Leopold Ilag; Ulrika Nilsson; Margareta Törnqvist; Natalia Tretyakova; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; amino acids; LC MS; fixed-charge derivatization; BMAA; chiral separation; pheromones; arctic aerosols; serum albumin adducts; benzo[a]pyrene diol epoxides; high-resolution MS; Analytical Chemistry; analytisk kemi;

   Abstract : Amino acids play vital roles in health, either in their native form or chemically modified. Some studies have linked certain non-proteinogenic amino acids to neurodegenerative diseases, such as in the case of β-methylaminoalanine (BMAA). READ MORE

7. 5. New Materials and Improved Ambient Techniques in Mass Spectrometry

   Author : Nicolò Riboni; Leopold Ilag; Elisa Robotti; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mass Spectrometry; Solid Phase Microextraction; Ambient Mass Spectrometry; Desorption Electrospray Ionization; Paper Spray Ionization; Cavitands; BTEX; New Psychoactive Substances; Analytical Chemistry; analytisk kemi;

   Abstract : Mass spectrometry (MS) is used in several fields, e.g. biology, environmental monitoring, medicine and forensics due to excellent qualitative and quantitative capabilities. The development of new instrumental setups and ionization sources is crucial to analyze a variety of compounds at trace levels. READ MORE