Search for dissertations about: "mass spectrometry - LC-MS MS"
Showing result 11 - 15 of 122 swedish dissertations containing the words mass spectrometry - LC-MS MS.
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11. Diagnosis of acute and chronic enteric fever using metabolomics
Abstract : Enteric (or typhoid) fever is a systemic infection mainly caused by Salmonella Typhi and Salmonella Paratyphi A. The disease is common in areas with poor water quality and insufficient sanitation. Humans are the only reservoir for transmission of the disease. READ MORE
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12. Secondary and Higher Order Structural Characterization of Peptides and Proteins by Mass Spectrometry
Abstract : The work in this thesis has demonstrated the advantages and limitations of using MS based technologies in protein and peptide structural studies. Tandem MS, specifically electron capture dissociation (ECD) have shown the ability to provide structural insights in molecules containing the slightest of all modifications (D-AA substitution). READ MORE
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13. Investigation of Modified Cellulose and Starch via Hydrolysis and Mass Spectrometry
Abstract : Starches and celluloses can be chemically modified in order to affect their physiochemical properties. Modification of these carbohydrate polymers entails derivatising their free hydroxyl groups with functional groups. READ MORE
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14. Liquid Chromatography-Mass Spectrometry as a Tool for Drug Metabolite Identification in Biological Fluids : With Application to Ketobemidone
Abstract : Electrospray ionization (ESI) mass spectrometry (MS) in combination with liquid chromatography (LC) is an excellent tool for the identification of drug metabolites. Utilizing this hyphenated technique in combination with proper sample pretreatment, the metabolic pathways of the analgesic drug ketobemidone were investigated in human urine and rat microdialysate from blood and brain. READ MORE
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15. Biomarkers of exposure to pesticides in humans
Abstract : Almost every human is exposed to pesticides, in work environments, by domestic use and via diet, drinking water and personal products. Current research expresses concern that low dose exposure over time can lead to adverse health effects. READ MORE