Search for dissertations about: "massive parallel sequencing"

Showing result 1 - 5 of 10 swedish dissertations containing the words massive parallel sequencing.

  1. 1. Tagging systems for sequencing large cohorts

    University dissertation from Stockholm

    Author : Mårten Neiman; KTH.; KTH.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; next generation sequencing; genotyping; massive parallel sequencing; 454; Pyrosequencing; amplicon sequencing; enrichment; DNA barcodes; NATURAL SCIENCES Biology Cell and molecular biology Genetics; NATURVETENSKAP Biologi Cell- och molekylärbiologi Genetik;

    Abstract : Advances in sequencing technologies constantly improves the throughput andaccuracy of sequencing instruments. Together with this development comes newdemands and opportunities to fully take advantage of the massive amounts of dataproduced within a sequence run. READ MORE

  2. 2. Enabling massive genomic and transcriptomic analysis

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Henrik Stranneheim; KTH.; [2011]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DNA; RNA; sequencing; massively parallel sequencing; alignment; assembly; single nucleotide polymorphism; LHON;

    Abstract : In recent years there have been tremendous advances in our ability to rapidly and cost-effectively sequence DNA. This has revolutionized the fields of genetics and biology, leading to a deeper understanding of the molecular events in life processes. READ MORE

  3. 3. Barcoded DNA Sequencing for Parallel Protein Detection

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Mahya Dezfouli; KTH.; KTH.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA barcoding; antibody labeling; antibody oligonucleotide bio-conjugation; DNAassisted proteomics; immuno-sequencing I-Seq ; droplet-based system; large-scale data analysis; Biotechnology; Bioteknologi;

    Abstract : The work presented in this thesis describes methodologies developed for integration and accurate interpretation of barcoded DNA, to empower large-scale-omics analysis. The objectives mainly aim at enabling multiplexed proteomic measurements in high-throughput format through DNA barcoding and massive parallel sequencing. READ MORE

  4. 4. Massively parallel analysis of cells and nucleic acids

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Julia Sandberg; KTH.; [2011]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Massively parallel sequencing; 454; Illumina; multiplex amplification; whole genome amplification; single cell; polyguanine; flow-cytometry;

    Abstract : Recent proceedings in biotechnology have enabled completely new avenues in life science research to be explored. By allowing increased parallelization an ever-increasing complexity of cell samples or experiments can be investigated in shorter time and at a lower cost. READ MORE

  5. 5. Methods for deep examination of DNA

    University dissertation from Stockholm : Karolinska Institutet, Dept of Medical Epidemiology and Biostatistics

    Author : Mårten Neiman; Karolinska Institutet.; Karolinska Institutet.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; massive parallel sequencing;

    Abstract : The development of sequencing technology has had a rapid pace during the last years and today, the sequencing instruments harbors enormous capacity. This thesis is about the development of methods to make the most out of this capacity and to use it for various applications. READ MORE