Search for dissertations about: "mast cell-deficient rat Ws Ws"

Found 1 swedish dissertation containing the words mast cell-deficient rat Ws Ws.

2. 1. Role of mast cell-derived mediators for leukocyte / endothelium-interactions and microvascular mechanisms in inflammation and in anaphylaxis

   Author : Yancai Guo; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Anaphylaxis; histamine; intravital microscopy; leukocyte; mast cell-deficient rat Ws Ws ; microdialysis;

   Abstract : The overall objective of this thesis was to study the roles of mast cell-derived mediators for leukocyte/endothelium interactions and microvascular mechanisms in inflammation and in anaphylaxis, using mast cell-deficient Ws/Ws rats and their wild-type +/+ littermates. The efflux of endogenous histamine and edema formation evoked by subplantar injection of compound 48/80 in rat hind-paws was dose-dependent in +/+ rats, and was essentially lacking in Ws/Ws rats. READ MORE