Search for dissertations about: "mast cells"

Showing result 1 - 5 of 171 swedish dissertations containing the words mast cells.

  1. 1. Mast Cells as Sentinels : Role of serglycin and mast cell proteases in infection and inflammation

    Author : Ananya Roy; Magnus Åbrink; Olaf Utermöhlen; Uppsala universitet; []
    Keywords : mast cells; serglycin; chymase; infection; parasite; Immunologi; Immunology;

    Abstract : Mast cells (MCs), normally classified into connective tissue MCs and mucosal MCs, are highly granulated cells found in the interface between the interior and the exterior environment of our body, e.g. skin, airways and gastro-intestinal tract. READ MORE

  2. 2. Induction of Mast Cell Apoptosis via Granule Permeabilization : A Novel Approach to Target Mast Cells

    Author : Aida Paivandy; Gunnar Pejler; Magda Babina; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Mast cells; Granules; Apoptosis; Reactive oxygen species; ROS; Lysosomotropic agents; Mefloquine; Immunologi; Immunology; Biokemi; Biochemistry;

    Abstract : Mast cells are densely granulated tissue-resident immune cells that play an important role in orchestrating inflammatory responses. Dysregulated increases in the numbers and activation status of mast cells can have deleterious consequences for the body in various inflammatory diseases. READ MORE

  3. 3. Mast cells in Hodgkin lymphoma : or 'What's a nice cell like you doing in a tumour like this?'

    Author : Marie Fischer; Gunnar Nilsson; Gunilla Enblad; Tor Olofsson; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Hodgkin lymphoma; mast cells; CD30; CD30L; IL-9; CCL5; atopic dermatitis; psoriasis; IL-8; Patologi; Pathology; Patologi;

    Abstract : Mast cell (MC) accumulation around tumours is an old observation gaining new relevance due to the multifaceted nature of MCs and their many roles in immunity, beyond allergy. Knowledge about tumour specific recruitment of, and interactions with, MCs is needed to unravel the function of their presence. READ MORE

  4. 4. Bystander Cells and Prognosis in Hodgkin Lymphoma

    Author : Daniel Molin; Stephen J. Proctor; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Hodgkin Lymphoma; Bystander cells; Eosinophilic granulocytes; Eosinophil cationic protein ECP ; Mast cells; Prognosis; Early and Intermediate stage; Onkologi; Hodgkin lymfom; eosinofila granulocyter; ECP; mast celler; prognos; tidiga och intermediära stadier; Oncology; Onkologi; Oncology; onkologi;

    Abstract : Hodgkin lymphoma (HL) is characterised histologically by a minority of malignant Hodgkin and Reed-Sternberg (HRS) cells surrounded by benign cells, and clinically by a relatively good prognosis. The treatment, however, leads to a risk of serious side effects. READ MORE

  5. 5. On the role of mast cells in chemokine-induced leukocyte recruitment

    Author : Yusheng Wang; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chemokines; mast cells; TNF-alpha; dexamethasone; P-selectin; E-selectin; activation; Medicine human and vertebrates ; endothelial cells; adhesion; Neutrophil; Medicin människa och djur ; recruitment;

    Abstract : Leukocyte recruitment is considered to playa key role in numerous inflammatory diseases. Tissue accumulation of Jeukocytes is a multi-steps process comprising rolling, adhesion and transmigration. READ MORE