Search for dissertations about: "mate"

Showing result 6 - 10 of 125 swedish dissertations containing the word mate.

  2. 6. Bound to the past: Historical contingency in aquatic microbial metacommunities

    Author : Máté Vass; Silke Langenheder; Steven Declerck; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; metacommunity; historical processes; priority effects; community assembly.; Biology with specialization in Limnology; Biologi med inriktning mot limnologi;

    Abstract : The composition of ecological communities differs due to a combination of different processes, which includes selection by local environmental conditions, dispersal from the regional species pool and random events. Additionally, historical processes such as past dispersal events may leave their imprint on communities as well, resulting in historically contingent communities. READ MORE

  4. 7. Development of phosphorus-containing metallo-β-lactamase inhibitors : Synthesis and binding studies by solution NMR and molecular docking

    Author : Katarzyna Palica; Máté Erdélyi; Christopher J. Schofield; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MBL inhibitors; antibiotic resistance; metallo-β-lactamases; NMR spectroscopy; Medicinal Chemistry; Läkemedelskemi;

    Abstract : The rapidly growing bacterial resistance development is turning into one of the main challenges of the 21st century. Our antibiotics are becoming ineffective for the treatment of bacterial infections, and without successful action, simple infections, such as pneumonia or Septicemia, will soon carry a highly probable mortal prognosis. READ MORE

  5. 8. Phosphonamidates as potential NDM-1 inhibitors

    Author : Katarzyna Palica; Mate Erdelyi; Lindon Moodie; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : WHO’s recent reports indicate that the rapidly growing resistance of bacteria became one of the biggest problems of the XXI century. The most powerful human counter weapon, antibiotics, starts to become ineffective for the treatment of bacterial infections. READ MORE

  6. 9. Characterising Halogen Bonding in a Cooperative Model System

    Author : Stefan Peintner; Mate Erdelyi; Anja Sandström; Uppsala universitet; []
    Keywords : Halogen Bond; NMR; peptide; conformation; RDC; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi;

    Abstract : Non-covalent interactions are the main driving factor for secondary structure formation of biomacromolecules and are of enormous importance for the direction of molecular recognition events, for example those of importance for drug discovery. Profound understanding of these interactions is of vital importance to achieve high affinity and selectivity of a ligand to a chosen target. READ MORE

  7. 10. Shape Matters : Characterization of Weak Interactions and Macrocycles by Conformational Analysis

    Author : Stefan Peintner; Máté Erdélyi; Oliver Zerbe; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : When studying conformational ensembles, it is most challenging to identify and characterize rapidly interconverting individual conformers. A precise description of the structural dynamics, however, rewards viable knowledge on conformation stabilizing forces as well as on the impact of external influences on the conformer composition. READ MORE