Search for dissertations about: "matrix metalloproteinase-9"

Showing result 16 - 20 of 24 swedish dissertations containing the words matrix metalloproteinase-9.

  2. 16. Systemic sclerosis : vascular, pulmonary and immunological aspects

    Author : Grethe Neumann Andersen; Solbritt Rantapää Dahlqvist; Lucia Mincheva-Nilsson; Sören Jacobsen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic sclerosis; interstitial lung disease; MMP-9; Th1 Th2; transcription factors; NO; iNOS; E-selectin; endothelium-dependent dilation; endothelium-independent dilation.; Rheumatology; Reumatologi;

    Abstract : In systemic sclerosis (SSc), interstitial lung disease (ILD) and engagement of the vascular system lead to increased morbidity and mortality. The aim of this thesis was to elucidate, in a consecutively included cohort of SSc (limited and diffuse) patients (n = 33), the T cell cytokine profile driving the disease in ILD and to explore the role of matrix metalloproteinase 9 (MMP-9) and its inhibitor: tissue inhibitor of metalloproteinase 1 (TIMP-1) in the extracellular matrix (ECM) degrading process leading to fibrous scarring and honey combing. READ MORE

  4. 17. The mucosal immune response against Helicobacter pylori infection

    Author : Sicheng Wen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : H. pylori infection affects more than half of the world’s population. The clinical consequences range from asymptomatic gastritis to peptic ulceration and gastric malignancy. H. READ MORE

  5. 18. Diesel exhaust and wood smoke : mechanisms, inflammation and intervention

    Author : Ala Muala; Thomas Sandström; Mark W Frampton; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Air pollution; deposition; bronchoscopy; Immunohistochemstry; filter; NO bioavailability; lungmedicin; Lung Medicine;

    Abstract : Background Particulate matter (PM) air pollution is associated with increased respiratory and cardiovascular morbidity and mortality. Diesel engine exhaust (DE) and wood combustion are major contributors to ambient air pollution and adverse health effects. READ MORE

  6. 19. Abdominal aortic aneurysm in women : risk factor profile and aneurysm wall

    Author : Christina Villard; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Abdominal aortic aneurysm (AAA) in women is rare; the prevalence is approximately 0.5% in elderly women, to compare with 2-4% in aging men. The few women that suffer from AAA are older and have a higher rupture risk. READ MORE

  7. 20. Leukocyte dysfunction and inflammatory markers in patients with chronic kidney disease and patients on dialysis

    Author : Jenny Olsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Patients with chronic kidney disease (CKD) and patients on dialysis are at risk for serious infectious complications. This is partly due to leukocyte dysfunction, which is a consequence of both uremic retention solutes and of dialysis. READ MORE