Search for dissertations about: "matrix-assisted laser desorption ionization mass spectrometry MALDI-MS"
Showing result 1 - 5 of 22 swedish dissertations containing the words matrix-assisted laser desorption ionization mass spectrometry MALDI-MS.
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1. Improved techniques for CE-MALDI-MS off-line coupling and MALDI-MS analysis of primarily hydrophobic proteins and peptides
Abstract : Due to the hydrophobic nature of integral membrane proteins (IMP) they give rise to several difficulties concerning handling and analysis, which is not the case for the most water soluble proteins. New analysis methods are needed, where the insolubility problems of the hydrophobic proteins due to aggregation and adhesion are tackled. READ MORE
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2. Electrophoretic focusing in microchannels combined with mass spectrometry : Applications on amyloid beta peptides
Abstract : Analysis of low-abundance components in small samples remains a challenge within bioanalytical chemistry, and new techniques for sample pretreatments followed by sensitive and informative detection are required. In this thesis, procedures for preconcentration and separation of proteins and peptides in open microchannels fabricated on silicon microchips are presented. READ MORE
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3. Tools for applied soft ionization mass spectrometry
Abstract : Mass spectrometry (MS) is an important analytical tool. Its most importantadvantages are sensitivity, resolution, and accurate and precise m/zmeasurements. To get the best results from an instrument, the user musthave knowledge of its limitation and requirements. READ MORE
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4. Improved techniques for CE and MALDI-MS including microfluidic hyphenations foranalysis of biomolecules
Abstract : In this thesis, improved techniques for biomolecule analysis using capillary electrophoresis (CE) and matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS) and hyphenations between those have been presented.A pre-concentration method which is possible to apply in both techniques, has also been investigated. READ MORE
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5. Development of Methods for Protein and Peptide Analysis Applied in Neuroscience Utilizing Mass Spectrometry
Abstract : This thesis describes the utilization of the matrix-assisted laser desorption ionization mass spectrometry (MALDI MS) and electrospray ionization (ESI) MS techniques for analysis of complex brain tissue samples. Direct molecular profiling of biological samples using MALDI MS is a powerful tool for identifying phenotypic markers. READ MORE