Search for dissertations about: "maturation in-vitro"

Showing result 11 - 15 of 158 swedish dissertations containing the words maturation in-vitro.

  2. 11. Generation of induced neurons via direct conversion in vivo and in vitro

    Author : Olof Torper; Neurobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cellular reprogramming; cell replacement therapies; induced dopaminergic neurons; in vivo reprogramming; Lentiviral vectors; AAV vectors;

    Abstract : Cellular reprogramming is when one cell is changed into another. This involves structural modifications on the DNA of a cell resulting in a transcriptional change. This occurs naturally during development when early pluripotent cells gradually differentiate into more specialized cells that finally result in a complete organism. READ MORE

  4. 12. Studies on the function of CD4CD25 regulatory T cells: An in vitro approach

    Author : Lukas Cederbom; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; CD152; Costimulation; Dendritic cells; Regulatory T cells; CD4 CD25 ; serology; transplantation; Immunologi; serologi;

    Abstract : Immunological self-tolerance is a state of the whole organism where deleterious responses are either avoided or regulated. Breaking of immunological tolerance will lead to autoimmune disease or chronic inflammatory conditions. READ MORE

  5. 13. EMBRYONIC GLIA AND FOREBRAIN NEUROGENESIS; in vitro generation and differentiation of telencephalic neurons

    Author : Charlotta Skogh; Neurobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; beta tubulin III; GFAP; RC2; Neurology; neuropsychology; neurofysiologi; DARPP-32; retinoic acid; serum; EGF; co-culture; cell culture; striatum; LGE; progenitor; precursor; radial glia; region specific; development; CNS; mouse; human; neurophysiology; Neurologi; neuropsykologi;

    Abstract : The current thesis is aimed to increase our understanding of the generation and differentiation of telencephalic neurons, with emphasis on the role of glial cells in these processes. Using in vitro methods we have studied the role of glial cells in neurogenesis, inheritance of genetic regional specification, and influence on differentiation of neurons. READ MORE

  6. 14. Oocyte maturation in a contaminated environment : effects of perfluoroalkyl substances on bovine early embryo development in vitro

    Author : Ida Hallberg; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Abstract : The content of this thesis is dedicated to female fertility, and more specifically the maturing oocyte. The aim was to investigate chemicals present in the direct environment of the oocyte and more specifically to investigate the sensitivity of the oocyte to perfluoroalkyl substances (PFASs) using a bovine in vitro embryo production model. READ MORE

  7. 15. Studies on the regulation and in vitro metabolic effects of leptin in children and adults

    Author : Amira M I Elimam; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Leptin; growth hormone; cortisol; Dexamethasone; insulin; fasting; total parenteral nutrition; meal timing; obese children; Prader Willi syndrome; adipocyte; lipolysis; lipogenesis.;

    Abstract : Leptin is a protein hormone secreted by adipocytes, which binds to receptors in the brain to affect food intake and energy expenditure. The leptin receptor is a member of the cytokine receptor family and is widely distributed in the body suggesting a broader role for leptin. READ MORE