Search for dissertations about: "mechanism of autophagy"

Showing result 1 - 5 of 42 swedish dissertations containing the words mechanism of autophagy.

  2. 1. Roles of membrane vesicles in bacterial pathogenesis

    Author : Svitlana Vdovikova; Sun Nyunt Wai; Richard Lundmark; Ann-Beth Jonsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Membrane vesicles; autophagy; pore-forming toxin; pore formation; Listeria monocytogenes; Vibrio cholerae; virulence factor; PrtV protease; listeriolysin O; V. cholerae cytolysin; mikrobiologi; Microbiology; molekylärbiologi; Molecular Biology;

    Abstract : The production of membranous vesicles is observed to occur among organisms from all domains of the tree of life spanning prokaryotes (bacteria, archaea) and eukaryotes (plants, animals and fungi). Bacterial release of membrane-derived vesicles (MVs) has been studied most extensively in cases of Gram-negative species and implicating their outer membrane in formation of extracellular MVs. READ MORE

  4. 2. Characterisation of autophagy pathways in atherosclerosis

    Author : Peter Saliba Gustafsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Atherosclerosis is an inflammatory disease of large to intermediate-sized arteries, characterised by retention of modified low-density lipoprotein within the vessel wall; this evokes an inflammatory response. Low-density lipoprotein carries lipids such as fatty acids, triglycerides and cholesterol, from the liver to peripheral tissues. READ MORE

  5. 3. Short and long-term regulation of autophagy

    Author : Patricia González-Rodríguez; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Autophagy is a conserved catabolic pathway triggered by stress conditions in which portions of the cytoplasm, damage organelles, misfolded proteins and intracellular bacteria are delivered and degraded in the lysosome/vacuoles. Thus, an efficient induction and completion of the process is required to ensure a proper homeostasis of the cell. READ MORE

  6. 4. The role of autophagy in anticancer therapy

    Author : Matheus Dyczynski; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Autophagy is a fundamental catabolic process, which is utilized by nearly every cell and tissue type upon stress exposure and has been shown to contribute to resistance to chemotherapy in a variety of cancers. The subject of this thesis is to shed light on the role of autophagy in chemotherapy and to investigate novel regulators of autophagy. READ MORE

  7. 5. Autophagy in Peripheral Neuropathy

    Author : Ayman Osman; Simin Mohseni; Lars-Göran Dahlin; David Engblom; Maria V Turkina; Kaj Fried; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Peripheral neuropathy includes a wide range of diseases affecting millions around the world, and many of these diseases have unknown etiology. Peripheral neuropathy in diabetes represents a large proportion of peripheral neuropathies. Nerve damage can also be caused by trauma. READ MORE