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Showing result 1 - 5 of 6 swedish dissertations matching the above criteria.

  1. 1. CRISPR based technologies for high-throughput metabolic engineering of yeast

    Author : Christos Skrekas; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cloning; Saccharomyces cerevisiae; enrichment; metabolic engineering; selection; library; screening; CRISPR; directed evolution;

    Abstract : The yeast Saccharomyces cerevisiae is a commonly used microorganism for metabolic engineering applications since it has a very well-studied metabolism and it can be easily genetically modified. This led to its use as a cell factory for the production of a wide variety of industrially relevant chemicals such as fuels, cosmetics and food additives. READ MORE

  2. 2. In vitro cellular models for neurotoxicity studies : neurons derived from P19 cells

    Author : Dina Popova; Jacobsson Stig O.P.; Anna Forsby; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurotoxicity; Neuronal cell culture; P19 cells; SH-SY5Y cells; βIII-tubulin; Methylmercury; Okadaic acid; Acrylamide; MDMA; Piperazine-derived designer drugs.;

    Abstract : Humans are exposed to a variety of chemicals including environmental pollutants, cosmetics, food preservatives and drugs. Some of these substances might be harmful to the human body. READ MORE

  3. 3. Clinical And Experimental Studies of Contact Allergy to Stent Metals - with focus on gold

    Author : Susanne Ekqvist; Yrkes- och miljödermatologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B-Au; patch testing; restenosis; contact allergy; Dermatology; metals; gold; stent; B-Ni; nickel;

    Abstract : A large number of patients are treated with coronary stents, and restenosis (recurrent narrowing of the vessel) is a serious problem. Contact allergy to metal ions eluted from stainless steel stents has been suggested to contribute to in-stent restenosis. READ MORE

  4. 4. Computer-assisted surgery in children

    Author : Magnus Anderberg; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; minimally invasive; learning curve; laparoscopy; fundoplication; da Vinci® Surgical System; costs; Children; computer-assisted; paediatric surgery; robot; robotic surgery;

    Abstract : Although positive in terms of patient trauma and recovery time, minimally invasive surgery has several technical drawbacks compared with open surgery. The new da Vinci® Surgical System from Intuitive Surgical® offers technical innovations aiming at overcoming these drawbacks and at improving the surgeon’s operating skills, such as the improved 3-D vision, tremor reduction and flexible instruments with a more natural and intuitive range of motion. READ MORE

  5. 5. Botulinum neurotoxins

    Author : Sara Persson Košenina; Pål Stenmark; Rongsheng Jin; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; botulinum neurotoxins; biokemi; Biochemistry;

    Abstract : Botulinum neurotoxins (BoNTs) are the most potent toxins known to man, with less than 1 μg of pure toxin being enough to kill an adult man. Despite the high toxicity, BoNTs are widely used in cosmetics and in medicine for the treatment of an increasing number of medical conditions. READ MORE