Search for dissertations about: "medical terms"

Showing result 16 - 20 of 982 swedish dissertations containing the words medical terms.

  1. 16. Development of Techniques for Characterization, Detection and Protein Profiling of Extracellular Vesicles

    Author : Sara Cavallaro; Jan Linnros; Apurba Dev; Hakho Lee; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular vesicles; streaming current; fluorescence microscopy; atomic force microscopy; scanning electron microscopy; protein profiling; size profiling; Biological and Biomedical Physics; Biologisk och biomedicinsk fysik;

    Abstract : Nanosized extracellular vesicles (EVs, ∼30-2000 nm) have emerged as important mediators of intercellular communication, offering opportunities for both diagnostics and therapeutics. In particular, small EVs generated from the endolysosomal pathway (∼30-150 nm), referred to as exosomes, have attracted interest as a suitable biomarker for cancer diagnostics and treatment monitoring based on minimally invasive liquid biopsies. READ MORE

  2. 17. RNA-based Prognostic Markers in Chronic Lymphocytic Leukemia

    Author : Marie Sevov; Richard Rosenquist; Mahmoud Mansouri; Denis Alexander; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chronic lymphocytic leukemia; prognostic markers; RNA-based markers; LPL; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Haematology; Hematologi; Medical Science; Medicinsk vetenskap;

    Abstract : Chronic lymphocytic leukemia (CLL) is a heterogeneous disease where a significant proportion of patients will develop an aggressive disease. Today, the mutational status of the immunoglobulin heavy variable (IGHV) genes is one of the strongest prognostic markers in CLL, where unmutated IGHV genes correlate with poor outcome. READ MORE

  3. 18. Affibody molecules targeting HER3 for cancer therapy

    Author : Tarek Bass; Stefan Ståhl; Christina Furebring; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Affibody molecule; cancer therapy; epidermal growth factor receptors; ErbB3; HER3; protein engineering;

    Abstract : The development of targeted therapy has contributed tremendously to the treatment of patients with cancer. The use of highly specific affinity proteins to target cancer cells has become a standard in treatment strategies for several different cancers. READ MORE

  4. 19. Towards UWB microwave hyperthermia for brain cancer treatment

    Author : Massimiliano Zanoli; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; treatment planning; microwave hyperthermia; brain cancer;

    Abstract : Despite numerous clinical trials demonstrating that microwave hyperthermia is a powerful adjuvant modality in the treatment of cancers, there have been few instances where this method has been applied to brain tumors. The reason is a combination of anatomical and physiological factors in this site that require an extra degree of accuracy and control in the thermal dose delivery which current systems are not able to provide. READ MORE

  5. 20. Superantigens in group A streptococcus : gene diversity and humoral immune response

    Author : Linda Maripuu; Mari Norgren; Susan Hollingshead; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Group A streptococcus; Streptococcus pyogenes; superantigen SAg ; SAg-gene profile; M-protein; emm-genotype; biomedicinsk laboratorievetenskap; biomedical laboratory science;

    Abstract : Group A streptococcus (GAS) is a strictly human pathogen that causes infections ranging from asymptomatic carriage to the highly lethal streptococcal toxic shock syndrome (STSS). GAS are classified according to the sequence of the variable 5’ end of the emm-gene that encodes the surface associated M-protein. READ MORE