Search for dissertations about: "medical virology"
Showing result 1 - 5 of 138 swedish dissertations containing the words medical virology.
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1. Adenovirus for Cancer Therapy : With a Focus on its Surface Modification
Abstract : Adenovirus serotype 5 (Ad5) is widely used as an oncolytic agent for cancer therapy. However, its infectivity is highly dependent on the expression level of coxsackievirus-adenovirus receptor (CAR) on the surface of tumor cells. READ MORE
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2. Functional characterization of the human adenovirus pVII protein and non-coding VA RNAI
Abstract : Human adenovirus (HAdV) is a common pathogen causing a broad spectrum of diseases. HAdV encodes the pVII protein, which is involved in nuclear delivery, protection and expression of viral DNA. To suppress the cellular interferon (IFN) and RNA interference (RNAi) systems, HAdVs encode non-coding virus-associated (VA) RNAs. READ MORE
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3. Oncolytic Adenovirus Therapy of Neuroendocrine Tumors
Abstract : Neuroendocrine tumors (NETs), originally described as carcinoids, represent a rare and heterogeneous group of neoplasms associated with intensive secretion of hormones, bioactive peptides and amines. Most of the patients are diagnosed at a late stage of disease, often with liver metastases. READ MORE
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4. The quest for new improved adenovirus gene therapy vectors against glioma tumours
Abstract : Gene therapy has received much attention the last decade as a method to correct a number of disorders arising from a defective gene. Gene therapy can be defined as the introduction of a functional genetic element into a cell for a therapeutic purpose. READ MORE
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5. Posttranscriptional Regulation of Human Papillomavirus Type 16 Late mRNAs
Abstract : The lifecycle of the human papillomavirus (HPV) is strictly linked to the programmed differentiation of the host cell it infects. Production of late proteins, which are used for the production of the major and minor capsid proteins, is only seen upon terminal differentiation of the epithelium. READ MORE