Search for dissertations about: "medullary thyroid cancer thesis"

Showing result 1 - 5 of 9 swedish dissertations containing the words medullary thyroid cancer thesis.

  2. 1. Transcriptional regulation of thyroid development possible interplay of endoderm- and mesoderm-derived morphogenetic signals

    Author : Jessica Westerlund; Göteborgs universitet; []
    Keywords : thyroid; congenital hypothyroidism; dysgenesis; Tbx1; Shh; Isl1; Foxa2; C-cells;

    Abstract : Congenital hypothyroidism (CH) affects 1 in 3000 children and is the major cause of treatable mental retardation. Most cases are due to malformations of the gland, collectively named thyroid dysgenesis. The disease results from defective thyroid organogenesis during embryonic life. READ MORE

  4. 2. Incidence and prognosis of differentiated thyroid cancer in Sweden

    Author : Catharina Ihre Lundgren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Differentiated thyroid cancer; papillary; follicular; nested case-control study; population-based; risk factors; prognosis; survival; TNM.;

    Abstract : Non-medullary differentiated thyroid cancer (DTC) is a rare disorder but, nevertheless, among the most common cancers in individuals below 40 years of age. DTC consists of papillary (PTC) and follicular (FTC) thyroid cancer. The prognosis is excellent with an overall 10-year survival of 90 %. READ MORE

  5. 3. Molecular genetic studies of human thyroid tumors

    Author : Tony Frisk; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Follicular thyroid tumors; tumor progression; Cowden disease; PTEN; CGH; RET; medullary thyroid carcinoma; MEN 2; anaplastic carcinoma.;

    Abstract : Tumors of the thyroid gland are common among the general population, but only a small proportion is malignant. The vast majority of thyroid tumors are benign, so called follicular adenomas. Sometimes subtypes such as atypical adenomas and adenomas with oxyphil, i.e. READ MORE

  6. 4. Behind the scenes of thyroid tumors : underlying genetic mechanisms

    Author : Jia Jing Lee; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Familial medullary thyroid cancer; follicular thyroid cancer; anaplastic thyroid cancer; CCND1; UBCH10; p16; RASSF1A; BRAF; array-CGH; tumor progression; global methylation; LINE-1; LUMA;

    Abstract : Thyroid cancer is the most frequently observed malignancy involving endocrine tissues. This group of diseases is also the major cause of death related to neoplasia of the endocrine system. Tumors in the thyroid gland are common in the general population and the majority represents benign follicular adenoma (FTA). READ MORE

  7. 5. Basic and translational studies of follicular thyroid neoplasia

    Author : Theodoros Foukakis; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Follicular thyroid cancer; follicular thyroid adenoma; PAX8-PPARgamma; PPARgamma; PTEN; RAS; RASSF1A; NORE1A; TERT; quantitative RT-PCR; microarray; cancer biomarker;

    Abstract : Thyroid tumors occur frequently in the general population and although the majority represents benign follicular adenomas (FTA), thyroid cancer constitutes 1% of all malignancies worldwide. Among the differentiated cancers, three main types are recognized, including the papillary and follicular forms (PTC and FTC) that originate from the follicular thyrocytes, and the medullary carcinoma that arises from the C-cells. READ MORE