Search for dissertations about: "meiosis"

Showing result 6 - 10 of 44 swedish dissertations containing the word meiosis.

  2. 6. Molecular analysis of protein complexes involved in pairing of mammalian chromosomes during meiosis

    Author : Jeanette Pelttari Danielsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : How is the accuracy of chromosomal pairing and segregation processes in dividing meiotic cells assured? This is an important question as premature or erratic segregation of chromosomes can give rise to aneuploidy, which is the leading genetic cause of pregnancy loss in humans. Meiosis is a cell division process that produces genetically unique haploid gametes from diploid cells. READ MORE

  4. 7. Molecular architecture of meiotic chromosomes

    Author : Ivana Novak; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Meiosis; Chromosome architecture; Synaptonemal complex; Cohesin complex;

    Abstract : Faithful chromosome segregation at each cell division is essential as the formation of cells with an abnormal number of chromosomes (aneuploid cells) can result in infertility, developmental defects or cancer. Aneuploidy occurs in approximately 20% of all conceptions, causing infertility and embryo death. READ MORE

  5. 8. Signaling pathways in the development of female germ cells

    Author : Deepak Adhikari; Kui Liu; Elisabet Stener-Victorin; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; ovary; primordial follicle; activation; mTORC₁; PI₃K; oocyte maturation; MPF; Cdk₁; medicinsk biokemi; Medical Biochemistry;

    Abstract : Primordial follicles are the first small follicles to appear in the mammalian ovary. Women are born with a fixed number of primordial follicles in the ovaries. Once formed, the pool of primordial follicles serves as a source of developing follicles and oocytes. READ MORE

  6. 9. The interplay between chromosome structure and meiotic integrity

    Author : Ingrid Lilienthal; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Sexually reproducing organisms employ a specialized cell division called meiosis to form unique, haploid gametes from a diploid precursor cell. Upon fertilization, two opposite-sex gametes fuse to create a zygote that will develop into the offspring. READ MORE

  7. 10. Mechanisms of unreduced gamete formation in Arabidopsis thaliana

    Author : Jun Yi; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Polyploidy is a widespread phenomenon in plants, which is commonly believed to arise through the production of unreduced (2n) gametes due to meiotic failure. Despite the importance of unreduced gamete formation for plant polyploidization, the mechanisms leading to their formation are not well understood. READ MORE