Search for dissertations about: "melanocytic"

Showing result 1 - 5 of 15 swedish dissertations containing the word melanocytic.

  2. 1. Tumor progression in melanocytic lesions : biological and diagnostic implications

    Author : Lena Kanter-Lewensohn; Karolinska Institutet; Karolinska Institutet; []
    Keywords : melanocytic tumors; MIB-1; Bcl-2; IGF-1R. p27; cyclins; cdks and Tamoxifen;

    Abstract : Cutaneous malignant melanoma has an annual incidence of 5% in Sweden, with about 1500 cases diagnosed yearly. In routine histopathology there are diagnostic difficulties in the analysis of pigmented lesions. READ MORE

  4. 2. Assessment of prognostic markers in benign and malignant melanocytic tumours

    Author : Vitalijs Svjatoha; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cutaneous melanoma is a malignant tumour that arises from pigmented skin cells – melanocytes, represents the most rapidly increasing cancer worldwide which is causing significant public health problem. During the past decade a significant progress has been made in the understanding of genesis and progression of melanocytic lesions. READ MORE

  5. 3. Sun exposure, prevalence and localization of common melanocytic naevi in Swedish children

    Author : Maria Karlsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: The rapidly rising incidence rates of cutaneous malignant melanoma call for more effective prevention strategies. Melanoma susceptibility is associated with having many common melanocytic naevi. Having fair skin, blonde/ash-blonde hair and grey/blue/green eye colour are also joint risk factors for melanoma and naevi. READ MORE

  6. 4. Identification and clinical evaluation of senescence-associated markers to distinguish melanocytic nevi from melanomas

    Author : Kyriakos Orfanidis; Ingrid Synnerstad; Jakob Wikström; John Paoli; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; senescence; nevi; melanoma; melanocytes; fibroblasts; ultraviolet UV radiation;

    Abstract : Melanoma is a form of cancer that develops in melanocytes. While it represents only 5% of skin malignancies, it is the most aggressive and lethal. Benign proliferation of these cells form the melanocytic nevi. The definitive diagnosis of melanocytic nevi or melanoma lesions is histopathologic. READ MORE

  7. 5. Analysis of Sun-Damaged Skin and Epidermal p53 Clones

    Author : Helena Bäckvall; Nicole Basset-Seguin; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Patologi; Pathology; Patologi; Pathology; patologi;

    Abstract : Sun-damaged skin is a relevant target tissue for studying the development of skin cancer. The aim of the present study was to investigate the epidermal response to ultraviolet radiation (UVR) in human skin in vivo and in vitro and to explore the mutagenic effect of UVA. READ MORE