Search for dissertations about: "melatonin"

Showing result 1 - 5 of 45 swedish dissertations containing the word melatonin.

  1. 1. Exploring Links between Melatonin, Inflammation and Depression

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Isak Sundberg; Uppsala universitet.; [2019]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; melatonin; inflammation; depression; biomarkers; cytokines; anxiety; hepatitis C; Psychiatry; Psykiatri;

    Abstract : Major depressive disorder (MDD) is one of the leading global causes of disease burden. Worse yet, about one third of the patients with MDD do not experience a remission with current treatments. READ MORE

  2. 2. Development and Validation of Bioanalytical Methods Application to Melatonin and Selected Anti-Infective Drugs

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Susanne Römsing; Uppsala universitet.; Högskolan Dalarna.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES Chemistry; NATURVETENSKAP Kemi; Analytical Chemistry; Analytisk kemi; african trypanosomiasis; melatonin; malaria; antiretroviral drugs; lumefantrine; tafenoquine; lamivudine; nevirapine; zidovudine; sampling paper; dried blood spots; capillary blood; antimalarial drugs; solid-phase extraction; liquid chromatography;

    Abstract : This thesis describes bioanalytical methods for measuring melatonin and some anti-infective drugs in biological fluids. Solid-phase extraction (SPE) or protein precipitation was used for enrichment and purification of the analytes and Liquid Chromatography (LC) was used to analyze the samples. READ MORE

  3. 3. Dietary L-Tryptophan Suppresses Aggression and Stress Responsiveness in Juvenile Rainbow Trout (Oncorhynchus mykiss) The Role of Brain Serotonin and Plasma Melatonin

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Olivier Lepage; Uppsala universitet.; [2004]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biology; serotonin; brain; fish; rainbow trout; Oncorhynchus mykiss; feed; stress; cortisol; melatonin; behaviour; aggression; Biologi; NATURAL SCIENCES Biology; NATURVETENSKAP Biologi;

    Abstract : Juvenile rainbow trout (Oncorhynchus mykiss) fed L-tryptophan (TRP) supplemented feed for 7 days show a suppression of aggressive behaviour along with a reduction in post-stress plasma cortisol levels. However, 3 days of elevated dietary TRP does not have any effects on either aggressive behaviour or post-stress plasma cortisol levels. READ MORE

  4. 4. The Duodenal Mucosal Bicarbonate Secretion Role of Melatonin in Neurohumoral Control and Cellular Signaling

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Markus Sjöblom; Uppsala universitet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; alkaline secretion; central nervous system; duodenal enterocyte; duodenal ulcer; duodenum; enterochromaffin cell; human; intraarterial; intracellular calcium; intracerebroventricular; melatonin; rat; vagal nerve; Fysiologi; MEDICINE Physiology and pharmacology Physiology; MEDICIN Fysiologi och farmakologi Fysiologi;

    Abstract : The duodenal lumen is exposed to aggressive factors with a high potential to cause damage to the mucosa. Bicarbonate secretion by the duodenal mucosa is accepted as the primary important defense mechanism against the hydrochloric acid intermittently expelled from the stomach. READ MORE

  5. 5. Role of Inducible Nitric Oxide Synthase and Melatonin in Regulation of β-cell Sensitivity to Cytokines

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Annika K. Andersson; Uppsala universitet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; β-cell; Cyclooxygenase; Cytokine; Diabetes; IFN-γ; IL-1β; iNOS; Insulin; Melatonin; Nitric oxide; Pancreatic islets; Phospholipase D; Prostaglandin E2; Streptozotocin; Cellbiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi;

    Abstract : The mechanisms of β-cell destruction leading to type 1 diabetes are complex and not yet fully understood, but infiltration of the islets of Langerhans by autoreactive immune cells is believed to be important. Activated macrophages and T-cells may then secrete cytokines and free radicals, which could selectively damage the β-cells. READ MORE