Search for dissertations about: "membrane channels"

Showing result 16 - 20 of 197 swedish dissertations containing the words membrane channels.

  2. 16. Integration and topology of membrane proteins

    Author : Carolina Boekel; Gunnar von Heijne; IngMarie Nilsson; Stephen High; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; insertion; Sec61; translocation; Biochemistry; Biokemi; biokemi; Biochemistry;

    Abstract : Membrane proteins comprise around 20-30% of most proteomes. They play important roles in most biochemical pathways. All receptors and ion channels are membrane proteins, which make them attractive targets for drug design. Membrane proteins insert and fold co-translationally into the endoplasmic reticular membrane of eukaryotic cells. READ MORE

  4. 17. The involvement of calcium and membrane fusion events in neutrophil secretion and respiratory burst

    Author : Daniel Granfeldt; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophils; calcium; regulated secretion; membrane fusion; SOC; arachidonic acid; intracellular fusion; oxygen free radicals; phagocytosis;

    Abstract : Neutrophil granulocytes play an important role in host defence during the early stages of microbial infection. The neutrophils have to leave the blood stream and migrate out into the tissue where they are able to phagocytose and kill microbes as well as dispose of cell debris from damaged tissues. READ MORE

  5. 18. Chloride Channels and Brown Fat Cells

    Author : Victor Sabanov; Jan Nedergaard; Bernd Nilius; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chloride channel; BAPTA; EGTA; Ca; Animal physiology; Zoofysiologi;

    Abstract : Chloride ion channels are macromolecular pores providing for passage of chloride ions (and certain other inorganic and organic anions) through the cell membrane, down their electrochemical gradients. Chloride channels are differentially expressed in various cells, to best suit specific cellular activities. READ MORE

  6. 19. Voltage-Sensor Domains of Ion Channels : Physiology, Regulation, and Role in Disease

    Author : Michelle Nilsson; Antonios Pantazis; Fredrik Elinder; Henry M. Colecraft; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Brain function depends on the ability of neurons to sense and respond to electricity, which is mediated by small modules in the neuronal membrane called voltage-sensor domains (VSDs). Disruption of VSD function can cause neurological disease such as epilepsy. READ MORE

  7. 20. Mathematical Modelling of Cerebral Metabolism : From Ion Channels to Metabolic Fluxes

    Author : Nicolas Sundqvist; Gunnar Cedersund; Maria Engström; Roland Nilsson; Sebastian Sten; João Duarte; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The brain is the most metabolically active organ in the human body and therefore rely on a continuous supply of oxygen and glucose. Neuronal stimulation in specific regions of the leads to the firing of action potentials, a process facilitated by voltage-gated ion channels in the neurons’ cell membranes. READ MORE