Search for dissertations about: "membrane orientation"

Showing result 1 - 5 of 55 swedish dissertations containing the words membrane orientation.

  2. 1. Membrane Orientation Studies with Polarized Light Spectroscopy

    Author : Malin Ardhammar; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; lipid vesicle; membrane orientation; flow linear dichroism; oriented circular dichroism;

    Abstract : Lipid vesicles are versatile tools in modern biophysical science. They can be used as models of the cell membrane, to examine permeability, stability and behavior of molecules in the bilayer. They may act as transporters in a pharmacological context, designed to deliver their cargo to a certain place in the patient. READ MORE

  4. 2. Model membranes for orientation and efflux studies

    Author : Malin Ardhammar; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; PNA; membrane orientation; linear dichroism; membrane penetration;

    Abstract : .... READ MORE

  5. 3. DNA-Controlled Lipid-Membrane Fusion

    Author : Lisa Simonsson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; exocytosis; vesicles; DNA; FRET; fluorescence resonance energy transfer; model system; total internal reflection fluorescence microscopy; TIRF microscopy; self-assembly; site-specificity; diffusion; biomembranes; lipid bilayer; membrane fusion;

    Abstract : Membrane fusion is essential for nerve-cell communication, for protein transport between cell organelles and the cell-membrane and for enabling the merger between virus and host membranes during virus infection. We have demonstrated that short DNA oligonucleotides, membrane-attached via CH in an orientation that mimics the overall zipperlike architecture of fusion-inducing proteins, induce fusion of both suspended vesicles and vesicles site-specifically tethered to SLBs. READ MORE

  6. 4. Polarized light spectroscopy studies of model membranes and DNA

    Author : Maxim Kogan; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; emission; ruthenium dipyridophenazine complex; lipid bilayer; linear dichroism; membrane model; membrane orientation; bimolecular probe; DNA;

    Abstract : Over the past decades Linear Dichroism (LD) spectroscopy has proven to be a powerful tool for studies of structure and functioning of different cell constituents, including DNA, cell membranes and proteins. Due to structural complexity of cell constituents, the LD studies of biomolecules depend on development of simplified model systems, which can mimic the original structure and functionality of the cell components. READ MORE

  7. 5. Self-assembly Strategies for Functional DNA Nanostructures

    Author : John Tumpane; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; carbon nanotube; polarised spectroscopy; nanotechnology; self-assembly; orientation; lipid membrane; gel electrophoresis; DNA;

    Abstract : The technological revolution of the twentieth century was famously subject to Moore’s law which related the rate of growth to the ability to scale-down the size of the components – size matters. Several decades later we are, however, approaching the limit of what is possible with silicon wafers. READ MORE