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Showing result 1 - 5 of 40 swedish dissertations matching the above criteria.

  2. 1. Model membranes for orientation and efflux studies

    Author : Malin Ardhammar; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; PNA; membrane orientation; linear dichroism; membrane penetration;

    Abstract : .... READ MORE

  4. 2. Interaction Between Antimicrobial Peptides and Phospholipid Membranes : Effects of Peptide Length and Composition

    Author : Lovisa Ringstad; Martin Malmsten; Per Hansson; Jeremy Ramsden; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adsorption; antibacterial; antimicrobial peptide; bilayer; ellipsometry; electrochemistry; electrostatic interactions; hydrophobicity; liposome; membrane; monolayer; phospholipid; secondary structure; supported bilayer.; PHARMACY; FARMACI; Pharmaceutical Physical Chemistry; farmaceutisk fysikalisk kemi;

    Abstract : Due to increasing problems with bacterial resistance development, there is a growing need for identifying new types of antibiotics. Antimicrobial peptides constitute an interesting group of substances for this purpose, since they are believed to act mainly by disrupting the bacterial membrane, which is a fast and non-specific mechanism. READ MORE

  5. 3. 5-Aminolevulinic acid and derivatives thereof : properties, lipid permeability and enzymatic reactions

    Author : Edvin Erdtman; Leif Eriksson; Tore Brinck; Örebro universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; 5-Aminolevulinic acid; tautomerization; PDT; DFT; MM; QM MM; Porphobilinogen synthase; Uroporphyrinogen III decarboxylase; membrane penetration; enzyme mechanism; Biophysical chemistry; Biofysikalisk kemi; Quantum chemistry; Kvantkemi; Theoretical chemistry; Teoretisk kemi; Fysikalisk kemi; Physical Chemistry; Biochemistry; Biokemi;

    Abstract : 5-aminolevulinic acid (5-ALA) and derivatives thereof are widely usedprodrugs in treatment of pre-malignant skin diseases of the cancer treatmentmethod photodynamic therapy (PDT). The target molecule in 5-ALAPDTis protoporphyrin IX (PpIX), which is synthesized endogenously from5-ALA via the heme pathway in the cell. READ MORE

  6. 4. Reconstitution of Membrane-Bound Enzymes for Neutron Scattering Studies: A Case Study of Human Dihydroorotate Dehydrogenase

    Author : Manuel Orozco; Molekylär cellbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; membrane proteins; dihydroorotate dehydrogenase; pyrimidine metabolism; neutron scattering; ubiquinone; QCM-D;

    Abstract : Membrane proteins are challenging to study due the necessity to maintain a lipid-like environment to preserve their structure and function. Particularly difficult to study are membrane-bound enzymes that interact with lipophilic substrates. READ MORE

  7. 5. Heat-Induced Cell Membrane Injury of Vegetable Tissues -An applied study on potatoes

    Author : Gerardo Gonzalez-M; Livsmedelsteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Livsmedelsteknik; Food and drink technology; PME; active transport; Cell membrane injury; potatoes;

    Abstract : Heat processing of vegetables involves the use of temperatures above the physiological limit which affect the cellular structures of the tissue and induce a series of events at cell level that will in turn be reflected in the transport properties of the tissue. One of the most important cellular structures from the mass transport point of view is the cell membrane since it represents the physical barrier to the transport of nutrients into and out of the cell. READ MORE