Search for dissertations about: "membrane protein insertion"

Showing result 11 - 15 of 69 swedish dissertations containing the words membrane protein insertion.

  2. 11. The interactome of the yeast mitochondrial ribosome : Organization of mitochondrial post-transcriptional regulation, membrane protein insertion and quality control

    Author : Braulio Vargas Möller-Hergt; Martin Ott; Michal Minczuk; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; mitochondrial post-transcriptional regulation; mitochondrial ribosome; membrane protein insertion; mitochondrial quality control; Biochemistry; biokemi;

    Abstract : The proteins found in mitochondria originate from two different genetic systems. Most mitochondrial proteins are synthesized in the cytosol and post-translationally imported into the organelle. However, a small subset of mitochondrial proteins is encoded in an organelle-resident genome. READ MORE

  4. 12. Marginally hydrophobic transmembrane α-helices shaping membrane protein folding

    Author : Tuuli Minttu Virkki de Marothy; Arne Elofsson; William Dowhan; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; membrane protein folding; hydrophobicity; translocon; transmembrane helix; marginally hydrophobic transmembrane helices; orientational preference; positive inside rule; aquaporin 1; Biochemistry; biokemi;

    Abstract : Most membrane proteins are inserted into the membrane co-translationally utilizing the translocon, which allows a sufficiently long and hydrophobic stretch of amino acids to partition into the membrane. However, X-ray structures of membrane proteins have revealed that some transmembrane helices (TMHs) are surprisingly hydrophilic. READ MORE

  5. 13. Integration and topology of membrane proteins

    Author : Carolina Boekel; Gunnar von Heijne; IngMarie Nilsson; Stephen High; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; insertion; Sec61; translocation; Biochemistry; Biokemi; biokemi; Biochemistry;

    Abstract : Membrane proteins comprise around 20-30% of most proteomes. They play important roles in most biochemical pathways. All receptors and ion channels are membrane proteins, which make them attractive targets for drug design. Membrane proteins insert and fold co-translationally into the endoplasmic reticular membrane of eukaryotic cells. READ MORE

  6. 14. Membrane chaperones : protein folding in the ER membrane

    Author : Jhansi Kota; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The plasma membrane (PM), comprised largely of lipids and proteins, is a dynamic structure that establishes the integrity of cells. Newly synthesized PM proteins are initially inserted into the endoplasmic reticulum (ER) prior to being targeted to the PM via the secretory pathway. Many PM proteins are polytopic, i.e. READ MORE

  7. 15. Membrane Protein Biogenesis in Saccharomyces cerevisiae

    Author : Johannes Reithinger; Gunnar von Heijne; Richard Zimmermann; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; biokemi;

    Abstract : Membranes are hydrophobic barriers that define the outer boundaries and internal compartments of living cells. Membrane proteins are the gates in these barriers, and they perform vital functions in the highly regulated transport of matter and information across membranes. READ MORE