Search for dissertations about: "membrane protein"

Showing result 1 - 5 of 1341 swedish dissertations containing the words membrane protein.

  1. 1. Advanced Fluorescence Microscopy to Study Plasma Membrane Protein Dynamics

    Author : Joachim Piguet; Horst Vogel; Ruud Hovius; Jerker Widengren; Antoine Triller; Switzerland Ecole Polytechnique Fédérale de Lausanne (EPFL); []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES; fluorescence; microscopy; plasma membrane; membrane proteins; membrane proteins diffusion; single-molecule imaging; single-molecule tracking; pentameric ligand-gated ion channels; nicotinic acetylcholine receptor; serotonin receptor; synapse; neuromuscular junction; post-synaptic scaffold; rapsyn; myopathies; fluorescent proteins; Förster resonance energy transfer; FRET imaging; protein-protein interactions; protein trafficking; photo-activatable proteins; Biologisk fysik; Biological Physics;

    Abstract : Membrane protein dynamics is of great importance for living organisms. The precise localization of proteins composing a synapse on the membrane facing a nerve terminus is essential for proper functioning of the nervous system. In muscle fibers, the nicotinic acetylcholine is densely packed under the motor nerve termini. READ MORE

  2. 2. Membrane protein topogenesis

    Author : Karin Öjemalm; Gunnar von Heijne; Tracy Palmer; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Abstract : The membranes of cells are highly complex and heterogeneous structures that fulfill multiple vital tasks. They form thin barriers that seal out the environment, thus defining the cell’s boundaries. READ MORE

  3. 3. Membrane-bound proteins : Characterization, evolution, and functional analysis

    Author : Misty M. Attwood; Helgi B. Schiöth; Arne Elofsson; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transmembrane protein; alpha-helical membrane protein; evolution membrane proteins; 3TM; 4TM; 5TM; trispanin; Bioinformatics; Bioinformatik;

    Abstract : Alpha-helical transmembrane proteins are important components of many essential cell processes including signal transduction, transport of molecules across membranes, protein and membrane trafficking, and structural and adhesion activities, amongst others. Their involvement in critical networks makes them the focus of interest in investigating disease pathways, as candidate drug targets, and in evolutionary analyses to identify homologous protein families and possible functional activities. READ MORE

  4. 4. Exploring the Interplay of Lipids and Membrane Proteins

    Author : Candan Ariöz; Åke Wieslander; Daniel O. Daley; Malcolm East; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; Membrane lipids; membrane proteins; anionic lipids; membrane remodeling; intracellular vesicles; model membrane systems; glycosyltransferase; Escherichia coli; lipid composition; fatty acid modification; membrane curvature; bacterial homeoviscous adaptation; biokemi; Biochemistry;

    Abstract : The interplay between lipids and membrane proteins is known to affect membrane protein topology and thus have significant effect (control) on their functions. In this PhD thesis, the influence of lipids on the membrane protein function was studied using three different membrane protein models. READ MORE

  5. 5. Enhancing membrane and secretory protein production yields in Escherichia coli

    Author : Zhe Zhang; Jan-Willem de Gier; Claes von Wachenfeldt; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; recombinant protein production; Escherichia coli; membrane protein; secretory protein; strain engineering; biokemi; Biochemistry;

    Abstract : Proteins fulfill essential functions in living cells. To produce sufficient amounts of a protein is essential to study the structure and function of a protein, or to use it for medical purposes. Escherichia coli is a Gram-negative bacterium that is widely used for recombinant protein production. READ MORE