Search for dissertations about: "membrane repair"

Showing result 16 - 20 of 50 swedish dissertations containing the words membrane repair.

  2. 16. Pathogenic effects of alpha-synuclein: modifications and toxicity

    Author : Natalie Landeck; Brain Repair and Imaging in Neural Systems (BRAINS); []
    Keywords : Parkinson s disease; adeno-associated viral vector; animal models; alpha-synuclein; substantia nigra; dopaminergic neurons; phosphorylation; aggregation; toxicity;

    Abstract : Accumulation of intraneuronal inclusions, containing mainly a protein called alpha-synuclein (asyn), is thought to play a critical role in neurodegenerative disorders such as Parkinson's disease (PD). In these so called Lewy bodies, the majority of asyn is phosphorylated at serine 129 (pS129) suggesting that post-translational modifications may play a critical role in the process of aggregate formation. READ MORE

  4. 17. Interactions between neural retina, retinal epithelium and choroid

    Author : Lena Ivert; Karolinska Institutet; Karolinska Institutet; []
    Keywords : RPE; neural retina; basal lamina; Bruch s membrane; choroid; subretinal space; bleb detachment; ICG; FAG; SLO; choroidal blood flow.;

    Abstract : The retinal pigment epithelium (RPE) is a non-replicating monolayer that plays a key role nursing the photoreceptors of the neural retina, regulating fluid movement within the subretinal space, maintaining a basal laminar layer of Bruch s membrane, and influencing the choriocapillaris. This project investigates how surgical manipulation of the retinal epithelial layer influences the neural retina, the choroid and the epithelial layer itself. READ MORE

  5. 18. Dealing with damaged lysosomes : Impact of lysosomal membrane stability in health and disease

    Author : Ida Eriksson; Karin Öllinger; Petra Wäster; Stig Linder; Daniel Wüstner; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The lysosome is the main unit for degradation and plays important roles in various cellular processes, such as nutrient sensing, cholesterol regulation and cell death. Consequently, altered lysosomal function contributes to, or even causes, several diseases. READ MORE

  6. 19. Micro- and Nanostructures for Studies of Model Biological Systems

    Author : Cassandra Niman; Fasta tillståndets fysik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Fysicumarkivet A:2014:Niman;

    Abstract : Sub-cellular biological components are complex systems that work together to control and maintain cellular activity and health. It is useful to study the basic elements that constitute the sub-cellular components using model systems, which mimic certain parts of the overall system, in order to better understand the system as a whole. READ MORE

  7. 20. Molecular Mechanisms Optimizing Photosynthesis during High Light Stress in Plants

    Author : Lan Yin; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Arabidopsis; light stress; photosynthesis; chloroplast;

    Abstract : Oxygenic photosynthesis is the process by which plants, algae and cyanobacteria use solar energy to convert water and carbon dioxide into molecular oxygen and carbohydrates. Photosynthesis sustains life on Earth since it provides not only energy for individual growth, but also represents the starting point of the food chain for most living organisms. READ MORE