Search for dissertations about: "memory B- cells"

Showing result 1 - 5 of 134 swedish dissertations containing the words memory B- cells.

2. 1. Approaches to analyses of cytotoxic cells. And studies of their role in H. pylori infection

   Author : Josef Azem; Göteborgs universitet; []
   Keywords : Helicobacter pylori; mucosal immunology; stomach; duodenum; asymptomatic; duodenal ulcer; gastric adenocarcinoma; NK cells; T cells; B cells; dendritic cells; cytotoxic;

   Abstract : Helicobacter pylori infection causes chronic gastritis that may progress to peptic ulcers or gastric adenocarcinoma and thereby cause major world-wide health problems. Previous studies have shown that CD4+ T cells and the production of the cytokine IFN- × are important components of the immune response to H. pylori in humans. READ MORE

4. 2. The role of B cells in rheumatoid arthritis

   Author : Maria Rehnberg; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B cells; Rheumatoid arthritis; B cell depletion therapy;

   Abstract : It has been known for a long time that B cells play a role in rheumatoid arthritis (RA). By production of autoantibodies, presentation of auto-antigens and by producing cytokines B cells may contribute to the pathogenesis of RA. In recent years it has been shown that anti-B cell therapy is a powerful tool in the treatment of RA. READ MORE

5. 3. Pinpointing biomarkers of importance for children with combined type 1 diabetes and celiac disease

   Author : Andrea Tompa; Maria Faresjö; Karin Åkesson; Mikael Karlsson; Jönköping University; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; celiac disease; children; biomarkers; immune markers; flow cytometry; cryopreservation; T cells; T-regulatory cells; B cells; B-regulatory cells; cytokines; chemokines; acute phase proteins; adipocytokines; matrix metalloproteinases;

   Abstract : Type 1 diabetes (T1D) and celiac disease are both characterized by an autoimmune feature. The diseases also share the same risk genes, and thereby patients have an increased risk of developing the other disease subsequently. READ MORE

6. 4. Peripheral immunity in patients with autoimmune endocrine diseases and the influence of physiological adaptions during pregnancy

   Author : Louise Magnusson; Per-Ola Carlsson; Rosaura Casas; Ola Winqvist; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Hashimoto´s thyroiditis; Graves´ disease; autoimmune Addison´s disease; antigen-presenting cells; B cells; non-classical monocytes; NK cells; memory CD8 T cells; CDCP1; SLAMF1; inflammation; lymphocyte activation; pregnancy; β-cell function; C-peptide; plasma proteome; prolactin; prokineticin-1; glucagon; oral glucose tolerance test; mass cytometry; proximity extension assay; Medicinsk vetenskap; Medical Science; Klinisk immunologi; Clinical Immunology; Endocrinology and Diabetology; Endokrinologi och Diabetologi; Obstetrik och gynekologi; Obstetrics and Gynaecology;

   Abstract : Type 1 diabetes (T1D), Hashimoto’s thyroiditis (HT), Graves’ disease (GD), and autoimmune Addison’s disease (AD) appear to share immunogenetic mechanisms. This idea is not novel, as “autoimmune tautology” is an established concept. READ MORE

7. 5. B cell subpopulations in the pathogenesis of rheumatoid arthritis

   Author : Katrin Thorarinsdottir; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B cells; Rheumatoid arthritis; Joint destruction; DAS28; CD21- low B cells;

   Abstract : B cell depleting therapy has proven to be an effective treatment in rheumatoid arthritis (RA), a disease characterized by the presence of autoantibodies against citrullinated proteins (ACPA) and the Fc portion of IgG (rheumatoid factor, RF). This demonstrates the vital role B cells play in the disease. READ MORE