Search for dissertations about: "mendelian genetics"
Showing result 1 - 5 of 24 swedish dissertations containing the words mendelian genetics.
-
1. Genetics of Two Mendelian Traits and Validation of Induced Pluripotent Stem Cell (iPSC) Technology for Disease Modeling
Abstract : Novel technologies for genome analysis have provided almost unlimited opportunities to uncover structural gene variants behind human disorders. Whole exome sequencing (WES) is especially useful for understanding rare Mendelian conditions, because it reduces the requirements for a priori clinical data, and can be applied on a small number of patients. READ MORE
-
2. Translational Research of Mendelian Disorders : Applications of Cutting-Edge Sequencing Techniques and Molecular Tools
Abstract : Up to 8% of all live-born children are affected with a congenital disorder. Some are Mendelian disorders of known etiology, but many are of undetermined genetic cause and mechanism, limiting diagnosis and treatment. READ MORE
-
3. Monogenic Traits Associated with Structural Variants in Chicken and Horse : Allelic and Phenotypic Diversity of Visually Appealing Traits
Abstract : Domestic animals have rich phenotypic diversity that can be explored to advance our understanding of the relationship between molecular genetics and phenotypic variation. Since the advent of second generation sequencing, it has become easier to identify structural variants and associate them with phenotypic outcomes. READ MORE
-
4. Genetic factors affecting pregnancy duration in humans
Abstract : This thesis investigates the mechanisms behind human pregnancy duration. Too short gestation is a direct cause of perinatal, neonatal, and infant mortality. Deviation from normal pregnancy length is also associated with a child's morbidity, even in the adulthood. READ MORE
-
5. Teaching genetics - a linguistic challenge : A classroom study of secondary teachers' talk about genes, traits and proteins
Abstract : The overall aim of this thesis is to investigate how teachers talk about genetics in actual classroom situations. An understanding of how language is used in action can give detailed information about how the subject matter is presented to the students as well as insights in linguistic challenges. READ MORE