Search for dissertations about: "mendelian randomization"
Showing result 6 - 10 of 33 swedish dissertations containing the words mendelian randomization.
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6. Beyond GWAS : Novel Methods and Resources for Genetic Epidemiology
Abstract : Since the first human genome assembly’s release, our knowledge of the genetic architecture of complex traits and diseases has grown steadily. Genome-wide association studies (GWAS) played a major role but are limited to common traits and single-nucleotide polymorphisms (SNPs). READ MORE
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7. Genetic Determinants of Obesity in Relation to Diet, Weight Gain and Mortality
Abstract : Obesity is one of the major health concerns that has reached epidemic proportions globally. It is generally believed to be a result of interactions between genetic and environmental factors. READ MORE
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8. Insulin Resistance : Causes, biomarkers and consequences
Abstract : The worldwide increasing number of persons affected by largely preventable diseases like diabetes demands better prevention and treatment. Insulin is required for effective utilisation of circulating nutrients. READ MORE
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9. Proteomic, metabolomic, and microbiome studies of blood pressure
Abstract : Hypertension is a major risk factor for cardiovascular disease and premature death with a substantial global economic burden. To prevent and treat hypertension, it is crucial to improve our understanding of the pathophysiological mechanisms. Hypertension is a multifactorial condition influenced both by genetic and environmental factors. READ MORE
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10. Elucidating causal relationships between energy homeostasis and cardiometabolic outcomes
Abstract : Energy metabolism dyshomeostasis is associated with multiple health problems. For example, abundant epidemiological data show that obesity and overweight increase the risk of cardiometabolic diseases and early mortality. READ MORE