Search for dissertations about: "menopausal status"

Showing result 1 - 5 of 28 swedish dissertations containing the words menopausal status.

  1. 1. Cholesterol metabolism in breast cancer: Prognostic factors and optimizing treatment

    Author : Maria Inasu; Bröstcancer - prevention & intervention; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Statins; Cholesterol; menopausal status; endocrine treatment; disease recurrence;

    Abstract : AbstractBreast cancer (BC) is the most common cancer among women in Sweden and worldwide. Adjuvant endocrine therapies are effective, yet 20-30% patients experience disease relapse. Altered cholesterol metabolism is an emerging hallmark of breast cancer proliferation and endocrine therapy resistance. READ MORE

  2. 2. Prospective studies of hormonal and life-style related factors and risk of cancer

    Author : Sara Wirén; Pär Stattin; Håkan Jonsson; Tanja Stocks; Alicja Wolk; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; epidemiology; androgens; risk factors; fatherhood status; dizygotic twins; height; cohort; case-control; prospective; Cancer Epidemiology; cancerepidemiologi;

    Abstract : Background: Androgens are important in prostate cancer development but how circulating levels of androgens affect risk of prostate cancer of different aggressiveness is not clear. Being childless has been associated with a lower risk of prostate cancer, but it is not clear if this association is causal or a result of residual confounding. READ MORE

  3. 3. Hip fracture : risk factors and mortality

    Author : Bahman Y Farahmand; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Epidemiology; case-control study; hip fracture; body size; physical activity; socioeconomic status; marital status; smoking; alcohol; survival;

    Abstract : The objective of this thesis was to identify factors related to risk of hip fracture and mortality after the hip fracture. We used data from a large population-based case-control study in postmenopausal women aged 50-81 years during 1993-1995 who resided in six counties in Sweden. READ MORE

  4. 4. Studies on the extracellular matrix of the dysfunctional pelvic floor

    Author : Marie Westergren Söderberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Pelvic floor; pelvic organ prolapse; stress urinary incontinence; extracellular matrix; collagen; SLRPs; decorin; lumican; fibromodulin; elastin associated proteins; fibrillin-1; fibulin-5; sex steroid hormone receptors; ER; PR; AR;

    Abstract : Objective: Pelvic floor dysfunction cause impaired quality of life of many women and is one of the most common reasons for gynaecological surgery on benign indications. Little is known about the pelvic floor extracellular matrix as a pre-requisite for mechanical sustainability through vaginal delivery, age and hormonal changes. READ MORE

  5. 5. Factors of impotance for women's health at midlife with special emphasis on effect by sex steroids

    Author : Cairu Li; Kardiovaskulär forskning - epidemiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; andrologi; reproduktion; reproduction; sexuality; Obstetrik; gynekologi; sexualitet; andrology; gynaecology; Obstetrics; lipids; carbohydrate metabolism; norethisterone acetate; estradiol; HRT; symptomatology; Menopause; midlife women;

    Abstract : Menopause is not a disease, but may bring about a wide range of health complaints and increase some risks of illnesses. The aim of this study was to evaluate the general health status and influences of background factors on symptomatology among a cohort of Swedish women aged 50-64 years, with specific emphasis on the effects of hormone replacement therapy (HRT) by investigating a profile of HRT use, long-term effects of HRT by different tapes and routes of administration as well as clinical and metabolic changes by use of low dose HRT. READ MORE