Search for dissertations about: "mesencephalon"

Showing result 1 - 5 of 29 swedish dissertations containing the word mesencephalon.

  1. 1. Dopamine neurons in ventral mesencephalon interactions with glia and locus coeruleus

    University dissertation from Umeå : Integrativ medicinsk biologi

    Author : Elisabet Berglöf; Umeå universitet.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson’s disease; ventral mesencephalon; nerve fiber formation; glia; locus coeruleus; grafting; antioxidant-enriched diet; MEDICINE Morphology; cell biology; pathology Morphology Histology; MEDICIN Morfologi; cellbiologi; patologi Morfologi Histologi;

    Abstract : Parkinson’s disease is a progressive neurodegenerative disorder, characterized by a depletion of the dopaminergic neurons in the substantia nigra. The cause of the disease is yet unknown but age, oxidative stress, and neuroinflammation are some of the features involved in the degeneration. READ MORE

  2. 2. Generation of midbrain dopaminergic neurons in vivo and in vitro: the role of Neurogenin2

    University dissertation from Department of Experimental Medical Science, Lund Univeristy

    Author : Elin Andersson; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; Medicin människa och djur ; cell replacement; Parkinson?s; dopamine; neuronal specification; development; mesencephalon; TH; neuronal differentiation; proneural genes; transcription factors; bHLH; neurospheres; stem cell; progenitor cell;

    Abstract : Parkinsons disease (PD) is a neurodegenerative disorder where dopaminergic neurons of the substantia nigra (SNc) in the mesencephalon are progressively eliminated. The ensuing loss of dopaminergic innervation of the basal ganglia manifests itself as severe motor deficits in PD patients. READ MORE

  3. 3. Parameters affecting the survival of cultured and grafted embryonic neurons

    University dissertation from Department of Experimental Medical Science, Lund Univeristy

    Author : Eva Maria Grasbon-Frodl; [1996]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lateral ganglionic eminence; striatum; Huntington s disease; lazaroids; reactive oxygen species; mesencephalon; Neural transplantation; Parkinson s disease; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Abstract : The extent of behavioral recovery following neural transplantation in part depends on the amount of surviving graft tissue. The main objective of this thesis was to study parameters affecting the survival of embryonic striatal and mesencephalic neurons in experimental models of Huntington's and Parkinson's disease. READ MORE

  4. 4. Somatosensory projection to the mesencephalon : an anatomical study in the cat and monkey

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Mikael Wiberg; Uppsala universitet.; [1986]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  5. 5. Characterization of human dopaminergic neurons in the developing mesencephalon and upon differentiation of stem cells- for replacement therapy in Parkinson´s disease

    University dissertation from Developmental Neurobiology

    Author : Jenny Nelander Wahlestedt; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson´s disease; stem cells; ventral mesencephalon; dopaminergic neurons; cell replacement therapy; human fetal tissue; radial glia; microRNA; BAC recombineering; reporter cell lines;

    Abstract : Cell-replacement therapy is a promising approach for treating patients with Parkinson ́s disease (PD). For this purpose, there is a need for developing a protocol that can generate high numbers of human transplantable mesencephalic dopaminer- gic (mesDA) neurons. READ MORE