Search for dissertations about: "mesenchymal tumor"

Showing result 1 - 5 of 60 swedish dissertations containing the words mesenchymal tumor.

  1. 1. Mesenchymal Stem Cells in Tumor Growth Inhibition and Cartilage Differentiation

    University dissertation from Department of Experimental Medical Science, Lund Univeristy

    Author : Laura Varas; Lund University.; Lunds universitet.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper; Medicine human and vertebrates ; Medicin människa och djur ; mesenchymal stem cell; Biomedical sciences; tumor growth inhibition; FGF2; cartilage; integrin alpha11beta1; integrin alpha10beta1;

    Abstract : The work presented in this thesis has been focused on mesenchymal stem cells (MSCs). In the two first studies, the effects of MSCs on tumor growth and development in vitro and in vivo was investigated. READ MORE

  2. 2. Platelets – Multifaceted players in tumor progression and vascular function

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Yanyu Zhang; Uppsala universitet.; Uppsala universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Tumor; Platelet; HRG; PDGFB; TBK1; NETs; Angiogenesis; EMT; Metastasis; Medicinsk vetenskap; Medical Science; Oncology; Onkologi; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi;

    Abstract : Platelets play a crucial role for blood hemostasis, the process that prevents bleeding. In addition, platelets have been demonstrated to promote cancer progression and cancer related complications like metastasis and thrombosis. READ MORE

  3. 3. Exploring immunotherapeutic targets in the tumor microenvironment

    University dissertation from Stockholm : Karolinska Institutet, Dept of Microbiology, Tumor and Cell Biology

    Author : Anna-Maria Georgoudaki; Karolinska Institutet.; Karolinska Institutet.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The immune system has developed along with the evolution of increasingly complex cellular organisms to sustain homeostasis and protect from threats. Cancer, a detrimental side effect of increasing organismic complexity, typically sequesters the immune system and hijacks its functions for its own prosperity. READ MORE

  4. 4. Genetic Characterization of Bone and Soft Tissue Tumors

    University dissertation from Department of Clinical Genetics, Lund University

    Author : Anna Dahlen; Lund University.; Lunds universitet.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical genetics; Klinisk genetik; cytogenetik; Genetik; cytogenetics; mesenchymal tumor; pericytoma; Genetics; chondroma; lipoma;

    Abstract : Bone and soft tissue tumors (BSTT) constitute a heterogeneous group of neoplasms of mesenchymal and neuroectodermal origin. Although many BSTT are rare, it has become clear that BSTT are characterized by recurrent acquired chromosomal aberrations, and the general aim of this thesis have been to apply molecular genetic and molecular cytogenetic techniques to further characterize recurrent breakpoints and deletions, and to search for candidate target genes. READ MORE

  5. 5. Importance of Hyaluronan-CD44 Signaling in Tumor Progression Crosstalk with TGFβ and PDGF-BB Signaling

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Helena Porsch; Uppsala universitet.; Uppsala universitet.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular matrix; growth factor; hyaluronan synthase; hyaluronidase; epithelial-mesenchymal transition; Molekylär cellbiologi; Molecular Cellbiology;

    Abstract : In order for solid tumors to metastasize, tumor cells must acquire the ability to invade the surrounding tissue and intravasate into blood- or lymph vessels, survive in the circulation and then extravasate at a distant site to form a new tumor. Overexpression of the glycosaminoglycan hyaluronan, and its adhesion receptor CD44, correlate with breast cancer progression. READ MORE