Search for dissertations about: "messengers"

Showing result 16 - 20 of 54 swedish dissertations containing the word messengers.

  2. 16. Plant Phosphoinositide Kinases. A Study of PtdIns 4-kinases and a PtdIns 4-phosphate 5-kinase

    Author : Tomas Westergren; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; regulation; plant phosphorylation; plasma membrane; lipid kinase; divalent ion; phosphoinositide; substrate specificity; Plant biochemistry; Växtbiokemi;

    Abstract : Phosphoinositides are of particular interest in signal transduction processes as they can be sequentially phosphorylated and used as precursors for the intracellular messengers inositol trisphosphate (InsP3) and diacylglycerol (DAG) that in turn affects calcium levels and protein kinase cascades, eventually leading to a physiological response. The activity and regulation of PtdIns 4-kinases and PtdInsP kinase was studied. READ MORE

  4. 17. Statistical models of TF/DNA interaction

    Author : Aymeric Fouquier d'Herouel; Erik Aurell; Otto Berg; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; gene expression; regulation; transcription factor; binding motif; matrix representations; gibbs sampling; binding affinity; non-specific binding; Biological physics; Biologisk fysik;

    Abstract : Gene expression is regulated in response to metabolic necessities and environmental changes throughout the life of a cell. A major part of this regulation is governed at the level of transcription, deciding whether messengers to specific genes are produced or not. READ MORE

  5. 18. PII proteins as global regulators of bacterial nitrogen metabolism

    Author : Pedro Filipe Teixeira; Stefan Nordlund; Ray Dixon; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Rhodospirillum rubrum; nitrogen metabolism; signal transduction; PII proteins; Biochemistry; Biokemi; Biochemistry; biokemi;

    Abstract : Nitrogen is an essential element to sustain life, being a component of most biological macromolecules. In spite of the abundance of gaseous N2, the availability of nitrogen compounds that can be readily used by most microorganisms is scarce and its production energetically demanding. READ MORE

  6. 19. Phagocytic-receptor signaling in human neutrophils

    Author : Ragnhild Löfgren; Matthias P. Wymann; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The neutrophil granulocyte is one of the most mobile cells in the body and through a number of functions represents the first line of defense against invading pathogens. Adhesion and chemotactic receptors on the cell surface work together through modulation of the cytoskeleton, thereby enabling cell movement. READ MORE

  7. 20. Exocytosis in Type 2 Diabetes- Functional and genetic studies of hormone secretion

    Author : Sofia A Andersson; Diabetes - öcellsexocytos; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 Diabetes; Insulin; Glucagon; Alpha-cells; Beta-cells; Exocytosis; Capacitance; SNARE; SNAP25; Syntaxin1A; Synaptotagmin; Munc-18 Stxbp1 ; SNP; Expression; miRNA;

    Abstract : Type 2 Diabetes (T2D) is characterized by dysregulated beta-and alpha-cell hormone secretion leading to elevated blood glucose levels. Several proteins are crucial in maintaining exocytosis of the hormone-containing granules such as Syntaxin1A (Stx1A), SNAP25, Munc-18 (Stxbp1) and the family of Synaptotagmins (Syts). READ MORE