Search for dissertations about: "metabolic genes"

Showing result 1 - 5 of 406 swedish dissertations containing the words metabolic genes.

  1. 1. Metabolic disorders : genes and mechanisms

    Author : Camilla Maffezzini; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Mitochondrial disorders constitute a subgroup of the large family of rare monogenic diseases called Inborn Errors of Metabolism (IEM), but defects in mitochondrial activity have also been reported in more common and complex pathologies. In the present thesis, I validate new disease-causing variants and study the underlying molecular defects in three different cases of IEM. READ MORE

  2. 2. Speciation and Metabolic rate : Insights from an avian hybrid zone

    Author : S. Eryn McFarlane; Anna Qvarnström; Jenny Boughman; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; resting metabolic rate; life history; hybridization; speciation; reproductive isolation; Ficedula flycatcher; Biologi med inriktning mot zooekologi; Biology with specialization in Animal Ecology;

    Abstract : The role of divergent climate adaptation in speciation has received surprisingly little scientific attention. My dissertation research focused on how resting metabolic rate (RMR) relates to the build up of prezygotic and postzygotic isolation in a natural Ficedula flycatcher hybrid zone. READ MORE

  3. 3. Molecular mechanisms in obesity-associated metabolic disease

    Author : Louise Olofsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : obesity; metabolic syndrome; cholesterol; resting metabolic rate; insulin resistance; serum amyloid A; S100 calcium binding protein A1; Zn-alpha2-glycoprotein; CCAAT enhancer binding protein alpha;

    Abstract : Obesity is associated with increased morbidity and mortality. Subjects with obesity are at risk of developing several serious conditions such as type 2 diabetes, hypertension, coronary heart disease and stroke. READ MORE

  4. 4. Metabolic variation in autoimmune diseases

    Author : Rasmus Kirkegaard Madsen; Johan Trygg; Thomas Moritz; Torbjörn Lundstedt; Matej Oresic; Umeå universitet; []
    Keywords : Rheumatoid Arthritis; Diabetes Mellitus type 1; Metabolic Profiling; Metabolomics; Chemometrics; Multivariate Data Analysis; Mass Spectrometry; biologisk kemi; biological chemistry;

    Abstract : The human being and other animals contain immensely complex biochemical processes that govern their function on a cellular level. It is estimated that several thousand small molecules (metabolites) are produced by various biochemical pathways in humans. READ MORE

  5. 5. Stolen genes, a shortcut to success : Evolution of metabolic and detoxification capacities in Diplomonads

    Author : Alejandro Jimenez-Gonzalez; Jan Andersson; Thomas A. Richards; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Diplomonads; Parasitism; Evolutionary Genomics; Metabolism; Lateral Gene Transfer;

    Abstract : Parasites do not represent a single evolutionary lineage meaning that they have evolved several times. The changes that parasites have undergone to adapt to such a lifestyle are not entirely understood. READ MORE