Search for dissertations about: "metabolic genes"

Showing result 6 - 10 of 417 swedish dissertations containing the words metabolic genes.

  2. 6. The metabolic syndrome : studies on thrifty genes

    Author : Katja Kannisto; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Adipose tissue; adiponectin; 11beta-hydroxysteroid dehydrogenase type 1; BMI; glucocorticoid; GLUT; HAART; HIV; IL-6; insulin; insulin resistance; LDL-cholesterol; leptin; lifestyle; lipodystrophy; LPL; obesity; PPAR; PGC-1; polymorphism; rosiglitazone; skeletal muscle; twins;

    Abstract : The metabolic syndrome consists of a cluster of atherogenic risk factors that include insulin resistance, glucose intolerance, hyperglycemia, dyslipidemia, obesity and a procoagulant state with impaired fibrinolysis. Genetic factors might predispose to the metabolic syndrome while the increasing prevalence of visceral and abdominal obesity linked to the shift to more sedentary lifestyles exacerbates the manifestation. READ MORE

  4. 7. Genetic epidemiological aspects of obesity and related traits. Human studies in Swedish and North-American cohorts

    Author : Peter Jacobson; Göteborgs universitet; []
    Keywords : Obesity; candidate genes; metabolic syndrome; resting metabolic rate; respiratory quotient; assortative mating;

    Abstract : Aims: To investigate two obesity candidate genes, the melanocortin-4 receptor (MC4R) and the adiponectin hormone (APM1), by screening their genomic sequences. To search the human genome for quantitative trait loci (QTLs) related to resting metabolic rate (RMR), and respiratory quotient (RQ). READ MORE

  5. 8. Exposure to Bisphenol A (BPA) and Metabolic Disruption

    Author : Linda Dunder; Monica Lind; Margareta Halin Lejonklou; Lars Lind; Anna-Maria Andersson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bisphenol A BPA ; Endocrine disrupting chemicals EDCs ; Developmental exposure; Metabolic disruption; Adipose tissue; Fatty acids; Insulin secretion; Experimental rat study; Epidemiology; Medicinsk vetenskap; Medical Science;

    Abstract : Metbolic disorders such as obesity, type 2 diabetes, liver lipid disorders and metabolic syndrome are increasing rapidly and have largely been attributed to genetic background and changes in diet, exercise and aging. However, there is now considerable evidence showing that other environmental factors, including environmental chemicals, may contribute to the rapid increase in the incidence of these metabolic diseases. READ MORE

  6. 9. Metabolic engineering of Saccharomyces cerevisiae for polyhydroxybutyrate production

    Author : Kanokarn Kocharin; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; S. cerevisiae; Acetyl-CoA; NADPH; Metabolic engineering; Polyhydroxybutyrate;

    Abstract : Establishing industrial biotechnology for the production of chemical compounds from the biosynthetic pathway has received a significant boost with the implementation of metabolic engineering. At present, metabolic engineering in Saccharomyces cerevisiae gains significant advantages of integration of knowledge acquired through a long history of use and data acquisition from novel –omics technologies hence enabling the development of a tailor-made S. READ MORE

  7. 10. Genetics of type 2 diabetes and the metabolic syndrome

    Author : Mia Klannemark; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; secreting systems; Endocrinology; PDE3B; PPARG; LPL; metabolic syndrome; diabetes; genetic; HSL; UCP2; Endokrinologi; sekretion; diabetologi;

    Abstract : Type 2 diabetes and the metabolic syndrome are highly prevalent disorders with severe complications such as cardiovascular disease. The aetiology of type 2 diabetes and the metabolic syndrome is not known, but the interaction between genetic factors and environmental triggers is important. READ MORE