Search for dissertations about: "metabolic profiling"

Showing result 1 - 5 of 49 swedish dissertations containing the words metabolic profiling.

  1. 1. Metabolic variation in autoimmune diseases

    University dissertation from Umeå : Umeå Universitet

    Author : Rasmus Kirkegaard Madsen; Johan Trygg; Thomas Moritz; Torbjörn Lundstedt; Matej Oresic; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Rheumatoid Arthritis; Diabetes Mellitus type 1; Metabolic Profiling; Metabolomics; Chemometrics; Multivariate Data Analysis; Mass Spectrometry; biologisk kemi; biological chemistry;

    Abstract : The human being and other animals contain immensely complex biochemical processes that govern their function on a cellular level. It is estimated that several thousand small molecules (metabolites) are produced by various biochemical pathways in humans. READ MORE

  2. 2. Processing and analysis of NMR data Impurity determination and metabolic profiling

    University dissertation from Stockholm : Institutionen för analytisk kemi

    Author : Jenny Forshed; Sven P. Jacobsson; Jules L. Griffin; [2005]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; quantitative nuclear magnetic resonance spectrometry; qNMR; multivariate analysis; peak alignment; data fusion; NATURAL SCIENCES Chemistry Analytical chemistry; NATURVETENSKAP Kemi Analytisk kemi;

    Abstract : This thesis describes the use of nuclear magnetic resonance (NMR) spectrometry as an analytical tool. The theory of NMR spectroscopy in general and quantitative NMR spectrometry (qNMR) in particular is described and the instrumental properties and parameter setups for qNMR measurements are discussed. READ MORE

  3. 3. Antibody based plasma protein profiling

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Ulrika Qundos; Jochen M. Schwenk; Peter Nilsson; Mathias Uhlén; Ulrike Korf; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein profiling; plasma; antibody; affinity proteomics; biomark- ers; multiplex; assay development;

    Abstract : This thesis is about protein profiling in serum and plasma using antibody suspension bead arrays for the analysis of biobanked samples and in the context of prostate cancer biomarker discovery. The influence of sample preparation methods on antibody based protein profiles were investigated (Papers I-III) and a prostate cancer candidate biomarker identified and verified (Papers III-V). READ MORE

  4. 4. Search for molecular and metabolic mechanisms contributing to impaired β-cell function

    University dissertation from Units of Epigenetics and Diabetes and Molecular Metabolism, Department of Clinical Sciences, Malmö

    Author : Siri Malmgren; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIF-1α; oxygen consumption; β-cell; Insulin secretion; Type 2 Diabetes; mitochondrial metabolism; metabolic profiling; Lipotoxicity; Histone acetylation; Histone methylation;

    Abstract : Type 2 Diabetes (T2D) prevalence is growing to pandemic proportions worldwide. The link between genotype, environment and β-cell function is still being investigated. READ MORE

  5. 5. Functional Profiling Of Metabolic Regulation In Marine Bacteria

    University dissertation from Växjö : Linnaeus University Press

    Author : Sarala Devi Muthusamy; Jarone Pinhassi; Torsten Thomas; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; marine microbiology; physiology; heterotrophic bacteria; adaptive strategies; survival; proteomics; growth phase; proteorhodopsin; inorganic sulphur oxidation; anaplerotic CO2 fixation; Miljövetenskap; Environmental Science;

    Abstract : Oceans are powered by active, metabolically diverse microorganisms, which are important in regulating biogeochemical cycles on Earth. Most of the ocean surface is often limited by nutrients, influencing bacterial growth and activities. READ MORE