Search for dissertations about: "metabolites"
Showing result 1 - 5 of 761 swedish dissertations containing the word metabolites.
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1. Progesterone metabolites : learning, tolerance, antagonism & metabolism
Abstract : Progesterone metabolites as allopregnanolone, isoallopregnanolone and tetrahydrodeoxy-corticosterone (THDOC) are increased in the luteal phase of the menstrual cycle, throughout pregnancy and during stress. Allopregnanolone and THDOC are neurosteroids with 3α-hydroxy, 5α-configurations and positive modulating effect on the GABAA receptor. READ MORE
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2. Drug Metabolites Formed by Cunninghamella Fungi : Mass Spectrometric Characterization and Production for use in Doping Control
Abstract : This thesis describes the in vitro production of drug metabolites using fungi of the Cunninghamella species. The metabolites were characterized with mainly liquid chromatography-mass spectrometry using ion-trap and quadrupole-time-of-flight instruments. A fungal in vitro model has several advantages e.g. READ MORE
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3. Pharmacokinetics and pharmacodynamics of pentoxifylline and metabolites
Abstract : Pentoxifylline is a haemorheologic drug with complex pharmacokinetics and pharmacodynamics due to both reversible metabolism and the formation of active metabolites. In humans, pentoxifylline is metabolised to at least seven phase 1 metabolites (M1-M7). READ MORE
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4. Volatile metabolites from microorganisms in indoor environments : sampling, analysis and identification
Abstract : Microorganisms are able to produce a wide variety of volatile organic compounds. This thesis deals with sampling, analysis and identification of such compounds, produced by microorganisms commonly found in buildings. READ MORE
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5. Polychlorinated biphenyls and their metabolites in human blood : Method development, identification and quantification
Abstract : PCBs are well known environmental pollutants. They are also precursors to metabolites, as the hydroxy-PCBs and the methylsulfonyl-PCBs. This thesis presents a validated methodology for analysis of PCB metabolites and a structural identification of 38 hydroxy-PCBs in human blood. READ MORE