Search for dissertations about: "metabolites"

Showing result 16 - 20 of 761 swedish dissertations containing the word metabolites.

  2. 16. Piperaquine - Bioanalys, drug metabolism and pharmacokinetics

    Author : Joel Tärning; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Piperaquine; malaria; Plasmodium falciparum; antimalarials; ACT; pharmacokinetics; NONMEM; population pharmacokinetics; NCA; bioavailability; enterohepatic circulation; metabolism; metabolites; animal models; bioanalysis; regression models; validation; HPLC; LC-MS MS; H-NMR; FTICR-MS;

    Abstract : Malaria is one of the most abundant parasitic diseases in the world affecting many of the poorest economies. The estimated prevalence is 300 to 700 million clinical episodes each year with up to 3 million deaths. READ MORE

  4. 17. Faecal Microbiota Transfer in Irritable Bowel Syndrome and Collagenous Colitis : Clinical outcomes and host-microbe interactions

    Author : Savanne Holster; Robert Jan Brummer; Julia König; Andreas Munk Petersen; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Faecal microbiota transfer; irritable bowel syndrome; collagenous colitis; gut microbiota; visceral sensitivity; host-microbe interactions; gene expression; metabolites;

    Abstract : Faecal microbiota transfer (FMT) aims at restoring a disturbed gut microbiotaby introducing faecal material from a healthy donor into a patient’s intestine. This approach is known as a safe and effective treatment in patients with recurrent Clostridioides difficile infection. READ MORE

  5. 18. Synthesis of organobromines as a tool for their characterisation and environmental occurrence assessment

    Author : Andreas Rydén; Göran Marsh; Vladimir Nikiforov; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Polybrominated diphenyl ethers; Brominated diphenyliodoniums salts; PBDEs; OH-PBDEs; MeO-PBDEs; Synthesis; Analysis; Abbreviations; Metabolites; Marine natural products; E-waste; Brominated flameretardants; miljökemi; Environmental Chemistry;

    Abstract : Polybrominated diphenyl ethers (PBDEs) have been intensively used as flame retardants (FRs) and have become ubiquitous environmental pollutants. PBDEs form hydroxylated PBDEs (OH-PBDEs) as metabolites. Further, some OH-PBDEs and methoxy-PBDEs (MeO-PBDEs) are natural products. READ MORE

  6. 19. New Bioanalytical Approaches, Magneto Immunoassays and SIRE Technology Based Biosensors

    Author : Kirstin Kriz; Tillämpad biokemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemical technology; Biokemisk teknik; antigens; superparamagnetic nanoparticles; magnetic inductance transducer; competitive magneto immunoassay; enzymes; metabolites; differential measurements; SIRE; biosensor;

    Abstract : This thesis presents two new technologies, SIRE technology based biosensors and magneto immunoassays, which can be used for bioanalytical applications. One of the main problems associated with biosensor technology is the instability of the recognition element since it is of biological origin and thus, has a limited lifetime. READ MORE

  7. 20. Aloe barbadensis Mill. as a therapeutic option for irritable bowel syndrome

    Author : Bani Ahluwalia; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aloe; Microbiota; Irritable Bowel Syndrome etiology; Irritable Bowel Syndrome therapy; Aloe barbadensis Mill.; Aloe; irritable bowel syndrome; metabolites; microbiota; prebiotic; immunosuppressive;

    Abstract : Irritable bowel syndrome (IBS) is a chronic and prevalent functional gastrointestinal disorder, with an incompletely understood pathophysiology. Because of the disease complexity and heterogeneity, the currently available treatment options for IBS are limited. READ MORE