Search for dissertations about: "metabotropic glutamate receptors"
Showing result 1 - 5 of 21 swedish dissertations containing the words metabotropic glutamate receptors.
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1. On the role of metabotropic glutamate receptors in motor control : analysis of synaptic, cellular and network properties
Abstract : The organization of neurons into neuronal networks is a basic feature of the central nervous system. An understanding of the function of neuronal networks requires knowledge on both synaptic connectivity and cellular properties. READ MORE
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2. Mechanisms in Tendon Healing : Pain, Biomarkers and the Role of Mast Cells
Abstract : Tendon injuries and tendinopathy are common disorders, but the underlying mechanisms are not well understood. The overall aim of this thesis was to better understand the mechanisms underlying tendon healing, pain, and inflammation. READ MORE
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3. Neuromodulation within a spinal locomotor network : role of metabotropic glutamate receptor subtypes
Abstract : The metabotropic glutamate receptors, mGluRs, are G-protein coupled receptors. They consist of eight cloned subtypes, which are divided into three groups depending on the amino acid sequence similarity, pharmacology and their signal pathways. READ MORE
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4. Cell-penetrating peptides : Uptake mechanism and the role of receptors
Abstract : Genes are the major regulators of biological processes in every living thing. Problems with gene regulation can cause serious problems for the organism; for example, most cancers have some kind of genetic component. Regulation of biological processes using oligonucleotides can potentially be a therapy for any ailment, not just cancer. READ MORE
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5. Structure-based Virtual Screening for Ligands of G Protein-coupled Receptors : Design of Allosteric and Dual-Target Modulators
Abstract : G protein-coupled receptors (GPCRs) are integral membrane proteins responsible for signal transduction of extracellular stimuli into the cell. Because of their widespread distribution throughout the human body and important roles in physiological processes, GPCRs are prominent drug targets and approximately 34% of all approved drugs interact with members of this superfamily. READ MORE