Search for dissertations about: "metal binding domains"

Showing result 1 - 5 of 11 swedish dissertations containing the words metal binding domains.

  1. 1. Development of a Yeast Model for Functional Analysis of Human Copper Transport Proteins

    Author : Kumaravel Ponnandai Schanmugavel; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; luminal loop; metal binding domains; Wilson’s disease protein; yeast model; ATP7B; copper transport.;

    Abstract : ABSTRACT Copper (Cu) is an important trace element that plays a vital role in several biological processes. It mediates numerous biochemical functions to maintain cellular homeostasis making it an essential metal for sustaining life. READ MORE

  2. 2. Adsorption of Molecules on Metal Surfaces Studied by High Resolution Core Level Photoemission

    Author : Andreas Beutler; Synkrotronljusfysik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Core level photoemission; molecules; adsorption; single crystal surfaces; metals; metal films; vibrations of adsorbed molecules; surface ordering; carbon monoxide; photoelectron spectroscopy; surface diffusion; Atomic and molecular physics; Atom- och molekylärfysik; Fysicumarkivet A:1998:Beutler;

    Abstract : Various aspects of the adsorption of molecules on metal surfaces have been studied making use of different properties of high resolution core level photoemission. A thorough investigation has been performed of the ordering and the site occupancy of CO overlayers on Rh(111). CO has been shown to adsorb in on-top and three-fold-hollow sites. READ MORE

  3. 3. Engineering Yeast for Functional Analysis of Human Cu Transport Proteins

    Author : Kumaravel Ponnandai Schanmugavel; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cu transport; yeast model; Atox1; genetic engineering; Wilson disease protein; ATP7B; complementation assay; yeast growth; metal-binding domain; mechanisms.;

    Abstract : ABSTRACT       Copper (Cu) is an important trace element that plays a vital role in several biological processes. Many proteins that are involved in various biochemical pathways require Cu as a cofactor. READ MORE

  4. 4. Structure and mechanism of iron and magnesium chelatases - at the heme-chlorophyll branch-point

    Author : Michel Fodje; Lunds universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biophysics; pi-helix; secondary structure; AAA; porphyrin metallation; chelatase; Molekylär biofysik;

    Abstract : Tetrapyrroles are synthesised through a single branched biosynthetic pathway. Heme and chlorophyll are synthesised from the common intermediate protoporphyrin IX at the heme-chlorophyll branch-point. READ MORE

  5. 5. Iron in Haem Biosynthesis. Structural Studies of Ferrochelatase and Frataxin

    Author : Tobias Karlberg; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Naturvetenskap; Natural science; Molekylär biofysik; Molecular biophysics; Biomedicinska vetenskaper; Biomedical sciences; protein crystallography; ferrochelatase; haem biosynthesis; iron; frataxin;

    Abstract : Ferrochelatase catalyses the synthesis of heme by inserting Fe(II) into protoporphyrin IX. The structure of ferrochelatase from yeast has been determined (2.4 Å). The structure is homodimeric with each of the monomer made up of two Rossmann type domains with an active-site cleft between them. READ MORE