Search for dissertations about: "metallo-beta-lactamases"

Found 4 swedish dissertations containing the word metallo-beta-lactamases.

  2. 1. Multidrug-Resistant Escherichia coli and Klebsiella pneumoniae : Treatment, Selection and International Spread

    Author : Thomas Tängdén; Otto Cars; Anders Johansson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Escherichia coli; Klebsiella pneumoniae; extended-spectrum beta-lactamases; carbapenemases; metallo-beta-lactamases; synergy; antibiotic interventions;

    Abstract : The prevalence of Escherichia coli and Klebsiella pneumoniae producing extended-spectrum beta-lactamases (ESBLs) and carbapenemases is increasing worldwide. Therapeutic options for infections with these bacteria are limited not only by the production of ESBLs and carbapenemases, which confer resistance to cephalosporins and carbapenems, but also by frequent co-resistance to other antibiotics. READ MORE

  4. 2. Antimicrobial Resistance and Production of Extended Spectrum Beta-Lactamases in Enterobacteriaceae from Birds in Bangladesh

    Author : Badrul Hasan; Björn Olsen; Åsa Melhus; Yvonne Agersø; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antimicrobial Resistance; ESBL; CTX-M; NDM; Poultry; Wild birds; E. coli; Bangladesh; Enterobacteriaceae; Antibiotics; Epidemiology; Epidemiologi; Mikrobiologi; Microbiology; Medical Science; Medicinsk vetenskap;

    Abstract : The dissemination of members of the Enterobacteriaceae family with extended spectrum beta-lactamases (ESBLs) and metallo-beta-lactamases (MBLs) has become a global concern. ESBLs and MBLs have been reported in humans, domestic animals, wildlife and the environment, and their isolation frequencies are increasing rapidly worldwide. READ MORE

  5. 3. Studies on the molecular mechanisms of resistance to fluoroquinolones and carbapenems in selected bacterial species

    Author : Nagwa Mustafa El Amin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The emergence of mutant bacteria with multi-resistant phenotype, no longer responsive to any of the available therapeutic agents is a growing concern. We have investigated the resistance mechanisms to two classes of antibacterials with broad spectrum of activity, carbapenems and fluoroquinolones. READ MORE

  6. 4. Beta-lactam and metronidazole resistance in the Bacteroides fragilis group

    Author : Hong Fang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Bacteroides fragilis group; beta-lactam; metronidazole; resistance; beta-lactamase; penicillinbinding proteins PBPs ; outer membrane proteins OMPs ;

    Abstract : The Bacteroides fragilis group organisms are anaerobic gram-negative bacilli. Ten species are currently included in this group. Members of the B. fragilis group are the major constituents of the normal colonic microflora and the most commonly encountered anaerobic bacteria in clinical specimens. READ MORE