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Found 5 swedish dissertations matching the above criteria.

  2. 1. Structural basis for metalloprotein catalysis : Characterization of Mycobacterium tuberculosis phosphatidylinositol phosphate synthase PgsA1 and Bacillus anthracis ribonucleotide reductase R2

    Author : Kristīne Grāve; Martin Högbom; Susanna Törnroth-Horsefield; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; biokemi;

    Abstract : About a third of all proteins need to associate with a particular metal ion or metallo-inorganic cofactor to function. This interplay expands the catalytic repertoire of enzymes and reflects the adaption of these catalytic macromolecules to the environments they have evolved in. READ MORE

  4. 2. Proton pathways in energy conversion : K-pathway analogs in O2- and NO-reductases

    Author : Nathalie Gonska; Pia Ädelroth; Alessandro Giuffré; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; heme-copper oxidase; cytochrome c oxidase; membrane protein; respiration; electron transfer; proton transfer; redox reaction; metalloprotein; non-heme iron; cytochrome ba3; flow-flash; carbon monoxide; liposome; respiratory control ratio; Biochemistry; biokemi;

    Abstract : Oxygen and nitric oxide reductases are enzymes found in aerobic and anaerobic respiration, respectively. Both enzyme groups belong to the superfamily of Heme-Copper Oxidases, which is further divided into several subgroups: oxygen-reducing enzymes into A-, B- and C-type and nitric oxide reductases into qNORs and cNORs. READ MORE

  5. 3. To metal, or not to metal : Diverse mechanisms of O2-activation and radical storage in the ferritin superfamily

    Author : Vivek Srinivas; Martin Högbom; Brian Hoffman; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Metalloprotein; di-metal; Oxygen activation; Substrate oxidation; Ribonucleotide reductase; Radical; DOPA; ADE-DOT; X-Ray free-electron laser; soluble Methane monooxygenase; Biochemistry; biokemi;

    Abstract : Proteins in the Ferritin-like superfamily are characterized by a four alpha-helical structural motif. These proteins are distributed across all three kingdoms of life and perform a wide range of functions. READ MORE

  6. 4. Ultrafast Structural and Electron Dynamics in Soft Matter Exposed to Intense X-ray Pulses

    Author : Olof Jönsson; Carl Caleman; Nicusor Timneanu; Olle Björneholm; Jörgen Larsson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; X-ray free-electron laser; Serial Femtosecond Crystallography; Radiation Damage; Plasma Simulations; Ultrafast Lasers; X-ray Imaging; Diffraction Theory; Ultrafast Phenomena; Hit Detection; Plasma Emission Spectra; Serial Femtosecond Crystallography; Protein Structure; Protein Crystallography; Metalloprotein; Non-thermal Heating; Water; Ferredoxin; NLTE Simulation; XFEL; FEL; SFX; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : Investigations of soft matter using ultrashort high intensity pulses have been made possible through the advent of X-ray free-electrons lasers. The last decade has seen the development of a new type of protein crystallography where femtosecond dynamics can be studied, and single particle imaging with atomic resolution is on the horizon. READ MORE

  7. 5. Computational protein crystallography : How to get the most out of your data

    Author : Justin Bergmann; Beräkningskemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Hirshfeld atom refinement HAR ; ; quantum refinement; protein crystallography; X-ray crystallography; neutron crystallography; nitrogenase; acetylcholin esterase; triose isomerase;

    Abstract : It is important to obtain accurate three dimensional structures of molecules and proteins to understand and predict their function and behaviour. X-ray crystallography is the major technique to determine three dimensional structures of proteins. READ MORE