Search for dissertations about: "metathesis"
Showing result 1 - 5 of 28 swedish dissertations containing the word metathesis.
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1. Structure-Based Design and Synthesis of Protease Inhibitors Using Cycloalkenes as Proline Bioisosteres and Combinatorial Syntheses of a Targeted Library
Abstract : Structure-based drug design and combinatorial chemistry play important roles in the search for new drugs, and both these elements of medicinal chemistry were included in the present studies. This thesis outlines the synthesis of protease inhibitors against thrombin and the HCV NS3 protease, as well as the synthesis of a combinatorial library using solid phase chemistry. READ MORE
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2. Synthesis of Polyhydroxylated Surfactants : Comparison of Surfactant Stereoisomers and Investigation of Haemolytic Activity
Abstract : I den här avhandlingen har vi studerat hur man kan göra nya tensider. En tensid är en speciell molekyl som har förmågan att lösa sig i både vatten och olja. Man kan göra följande experiment hemma: Fyll en glasburk till hälften med vatten och tillsätt en droppe matolja. READ MORE
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3. Design and Synthesis of Serine and Aspartic Protease Inhibitors
Abstract : This thesis describes the design and synthesis of compounds that areintended to inhibit serine and aspartic proteases. The first part of the text deals with preparation of inhibitors of the hepatitis C virus (HCV) NS3 serine protease. Hepatitis C is predominantly a chronic disease that afflicts about 170 million people worldwide. READ MORE
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4. Amino Aacohols : stereoselective synthesis and applications in diversity-oriented synthesis
Abstract : This thesis is divided into three separate parts with amino alcohols as the common feature. The first part describes the development of a novel three-component approach to the synthesis of α-hydroxy-β-amino esters. READ MORE
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5. Secondary Interactions in Symmetric Double Bond Formation Catalysed by Molecular Ruthenium Complexes
Abstract : Chemistry has a tremendous impact on everyone’s life, although society does not always realize its power and ubiquity. In recent years, improved economy and sustainability of chemical processes has become a worldwide priority. READ MORE