Search for dissertations about: "metformin"
Showing result 16 - 20 of 34 swedish dissertations containing the word metformin.
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16. On anti-diabetic agents and the vasculature
Abstract : Diabetes is rapidly increasing worldwide, and the number of patients suffering from diabetes is projected to rise with 50 % over the next 25 years, then affecting almost 600 million adults. Type 2 diabetes comprises 90-95 % of all people with diabetes, and they constitute a patient group that carries a high burden of cardiovascular disease. READ MORE
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17. Towards a Health Economic Simulation Model of Type 2 Diabetes in Sweden
Abstract : The aim of this thesis was to provide part of the data required in updating/developing computer simulation models (CSMs) for type 2 diabetes mellitus (T2DM) using data obtained from routine clinical practice in Sweden. In paper I, evolution of five biomarkers (i.e. READ MORE
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18. Adipose tissue inflammation, hepatic fat accumulation and insulin resistance
Abstract : Insulin resistance is the central feature of a variety of metabolic disorders, such as type 2 diabetes and the metabolic syndrome. The incidence of these disorders, often together with obesity, is currently increasing throughout the world. READ MORE
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19. Insulin signaling and glucose transport in insulin resistant human skeletal muscle
Abstract : Insulin resistance in skeletal muscle is a hallmark feature of Type 2 diabetes mellitus. The overall aim of this thesis was to investigate downstream intermediates in the insulin signaling pathway in an attempt to characterize the molecular mechanism of skeletal muscle insulin resistance in Type 2 diabetes. READ MORE
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20. Stem cell in-vitro strategies for the induction of sensory neurons for inner ear cell therapy
Abstract : The cochlea, a part of the auditory system, is a complex structure consisting of several different types of cells including hair cells and spiral ganglion neurons. In mammals, the regenerative potential of hair cells and spiral ganglion neurons is lost soon after the birth and damage to any of these cells causes sensorineural hearing loss. READ MORE