Search for dissertations about: "methacholine challenge"

Showing result 1 - 5 of 15 swedish dissertations containing the words methacholine challenge.

  1. 1. Optimizing and evaluation of a methacholine provocation test with application in occupational research

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Britt-Marie Sundblad; Uppsala universitet.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; Airway responsiveness; methacholine provocation; nitric oxide; eucapnic hyperventilation; organic dust; Fysiologi; MEDICINE Physiology and pharmacology Physiology; MEDICIN Fysiologi och farmakologi Fysiologi; Physiology; fysiologi;

    Abstract : We have developed a methacholine provocation method, which detects bronchial responsiveness in more than 80% of healthy subjects. The method enables us to detect differences in bronchial responsiveness within the normal range. With this method FEV1 and Gaw had similar sensitivity in detecting small differences in bronchial responsiveness. READ MORE

  2. 2. Laboratory animal allergy, Long-term incidence, effects on lung function, individual risk factors

    University dissertation from Department of Social Medicine, Panum Institute, University of Copenhagen, Blegdamsvej 3, DK-2200 Copenhagen N, Denmark

    Author : Lars Sjöstedt; [1996]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serum IgE; occupational asthma; methacholine challenge; lung function; laboratory animal work; LAA; HLA-linked immunosuppression; HLA-DR4; HLA-B16; Gm allotypes; genetic markers; atopic allergy; Airway responsiveness; animal allergens; skin prick testing; small airways.; Occupational health; industrial medicine; Yrkesmedicin; arbetsmiljömedicin;

    Abstract : The aim was to study and prospectively follow symptoms and sensitisation of laboratory animal workers with laboratory animal allergy (LAA) and workers at risk for development of LAA in terms of latency time, incidence, prevalence and possible health selection. Furthermore, the impact of animal positive skin prick tests (SPT) on lung function and individual risk factors for development of LAA was studied. READ MORE

  3. 3. The asthmatic airway response – effects on physiology and biomarkers

    University dissertation from Lund University: Faculty of Medicine

    Author : Henning Stenberg; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asthma; Exhaled breath temperature; Exercise; Allergen challenge; Small airways; Airway provocations; Spirometry; Impulse oscillometry; Inert gas washout; Body plethysmography; Club cell protein CC16 ;

    Abstract : Asthma is a common airway inflammatory disease, associated with a variable degree of airway obstruction. It is a heterogeneous condition with large variations in severity and clinical presentation. Moreover, disease activity can vary from time to time. Taken together, these factors make the diagnosis, monitoring and treatment of asthma challenging. READ MORE

  4. 4. Effect of allergen specific immunotherapy on allergic inflammation in the upper and lower airways

    University dissertation from Göteborg : Göteborgs Universitet

    Author : Monica Arvidsson; Göteborgs universitet.; Gothenburg University.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; birch pollen allergy; cat allergy; specific immunotherapy; rush immunotherapy; experimental allergen challenge; late asthmatic response;

    Abstract : Experimental allergen challenge is widely used in diagnostic practice and research in allergy, but its relationship to environmental exposures is not clarified. Both models of allergic diseases have been used in order to examine the effects of allergen specific immunotherapy (SIT). READ MORE

  5. 5. Clinical studies of asthma phenotypes focusing on the role of the leukotrienes

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine

    Author : Per Gyllfors; Karolinska Institutet.; Karolinska Institutet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; >asthma; aspirin intolerance; leukotrienes; leukotriene D4 responsiveness; methacholine responsiveness; exhaled nitric oxide;

    Abstract : Inflammation in the airways in connection to asthma is a complex phenomenon and the mechanisms underlying the associated clinical symptoms involve the interaction of many different kinds of cells and mediators, giving rise to different phenotypes. The aim of the present thesis was to investigate the molecular and cellular mechanisms that results in two of these phenotypes, i. READ MORE