Search for dissertations about: "methylation array"

Showing result 21 - 25 of 29 swedish dissertations containing the words methylation array.

  2. 21. Prognostic and biological implications of epigenetic changes in leukemia

    Author : Stefan Deneberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The field of epigenetic research in hematology and oncology is rapidly expanding. Even so, reliable data linking epigenetic changes to clinical outcomes are scarce. We conducted two retrospective studies in AML. READ MORE

  4. 22. Molecular Genetic Characterization of Acute Lymphoblastic Leukemia with a Poor Prognosis

    Author : Setareh Safavi; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute lymphoblastic leukemia; hypodiploidy; adult acute lymphoblastic leukemia;

    Abstract : Acute lymphoblastic leukemia (ALL) affects individuals at all ages, with peak incidences in children 50 years. ALL is broadly categorized into B-cell precursor (BCP) and T-cell ALL with specific clinical features associated with outcome. READ MORE

  5. 23. CANCER-RELATED GENE REGULATION MECHANISMS

    Author : Srinivas Veerla; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Cancer is a disease characterized by deregulation of cellular functions. The means by which these changes occur may differ among cancer types. However, common to all cancers are that they have changed the genetic programs that determine their characteristics. Genetic programs are mainly regulated by the action of transcription factors. READ MORE

  6. 24. Comparative bioinformatics analyses of transcriptome and epigenome data using bovine model systems

    Author : Naveed Jhamat; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Bioinformatics methodology is used to understand complex biological processes in molecular biology, genetics and epigenetics. This thesis performed analysis of the complex biological processes controlling reproduction in mammals including dairy cattle. READ MORE

  7. 25. Molecular studies of endocrine tumors : Insights from genetics and epigenetics

    Author : Samuel Backman; Per Hellman; Peter Stålberg; Olov Norlén; Robert Bränström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroendocrine tumors; Carcinoid; Pheochromocytoma; Aldosterone; Cancer; MEN1; Multiple endocrine neoplasia; Medicinsk vetenskap; Medical Science;

    Abstract : Endocrine tumors may be benign or malignant and may occur in any of the hormone producing tissues. They share several biological characteristics, including a low mutation-burden, and may co-occur in several hereditary tumor syndromes. The aim of this thesis was to identify genetic and epigenetic aberrations in endocrine tumors. READ MORE