Search for dissertations about: "methylmalonic acid"

Found 5 swedish dissertations containing the words methylmalonic acid.

  1. 1. Vitamin B12 and folate depletion in the elderly. Diagnosis, clinical correlates and causes

    Author : Catharina Lewerin; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aged; methylmalonic acid; homocysteine; vitamin B12; folic acid; renal function; cognition; movement; atrophic gastritis;

    Abstract : Subclinical vitamin B12 and folate deficiency is common in the elderly. The clinical significance remains unresolved. There is not a universally accepted set of laboratory criteria for diagnosis, however subclinical deficiency is important to diagnose since it is easy to treat. READ MORE

  2. 2. Cobalamin/folate status and its relation to cognition and behaviour in psychogeriatric patients

    Author : Karin Nilsson; Lund Psykiatri; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; klinisk psykologi; Psykiatri; psychosomatics; clinical psychology; Psychiatry; folate; Cobalamin; homocysteine; methylmalonic acid; dementia; psychogeriatric patients; delirium; psykosomatik;

    Abstract : The aim of this study was to evaluate the diagnostic potentials of four different biochemical markers, serum cobalamin, blood folate, plasma homocysteine and serum methylmalonic acid for diagnosis of cobalamin/folate deficiency in a psychogeriatric population. The second aim was to investigate the relationship between these markers and various clinical and functional parameters of the nervous system in patients with dementia disorders. READ MORE

  3. 3. Urologic and metabolic consequences of continent urostomy (Kock reservoir) in children and adolescents

    Author : Gamal Abd El-Gawad; Göteborgs universitet; []
    Keywords : Urinary diversion; Continent ileal urostomy; Kock pouch; Complication; Enterocystography; Enterocystometry; Urography; B12; Folic acid; MMA; Quality of life.;

    Abstract : During the last decades, urinary diversion using an intestinal segment has been commonly used in children and adolescents. Kock pouch is a feasible alternative for the children in need of a continent diversion where other alternatives such as Mitrofanoff are excluded for various reasons. READ MORE

  4. 4. Studies on the regulatory roles of cholesterol and bile acids

    Author : Charlotte Murphy; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cholesterol; cholic acid; bile acids; cholesterol homeostasis; squalene epoxidase; mevalonate kinase; cob I alamin adenotransferase; SREBP; NF-Y;

    Abstract : Cholesterol is essential for normal growth and development in mammals. However, excess cholesterol can be harmful leading to diseases such as atherosclerosis and gallstones. Once formed the ring structure of cholesterol cannot be catabolised by the body and must therefore be converted to other compounds for excretion. READ MORE

  5. 5. Studies on Vitamin B12 and Folate Deficiency Markers in the Elderly : A Population-based Study

    Author : Karin Björkegren; Kurt Svärdsudd; Åke Schwan; Herman Nilsson-Ehle; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Cobalamin; folate; MMA; tHcy; multivitamin; symptoms; survey; treatment trial; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Family Medicine; Allmänmedicin;

    Abstract : The aims of this study were to document the levels of cobalamin, folate, methylmalonic acid (MMA) and total homocysteine (tHcy) in serum and their relations to symptoms, clinical findings, and other factors in order to improve the possibilities of detecting early deficiency of vitamin B12 or folate, and to study the effects of cobalamin and folic acid treatment over a three-year period. The study population consisted of a 20% random sample of persons 70 years or older living in Älvkarleby in mid-Sweden. READ MORE