Search for dissertations about: "methylphenidate"

Showing result 1 - 5 of 10 swedish dissertations containing the word methylphenidate.

  2. 1. Interrogation of drug effects on the lipid composition of single cells and Drosophila brain using ToF-SIMS imaging

    Author : Thuy Mai Hoang Philipsen; Chalmers tekniska högskola; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Drosophila melanogaster; Keywords: Mass spectrometry imaging; PC12 cell.; ToF-SIMS; zinc deficiency; lipid change; methylphenidate; cocaine; cognition; omega-3 and 6- fatty acids;

    Abstract : Lipids are essential for all living organisms on Earth. The most important function of lipids is that they act as the building blocks of cellular membranes. Lipids consist of polar head groups and non-polar tail groups and assemble into bilayer structures to create cell and organelle membranes. READ MORE

  4. 2. Mass spectrometry based analysis of drugs, neurotransmitters and lipids in invertebrate model systems

    Author : Nhu TN Phan; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; CE-MS; Imaging mass spectrometry; Lipids; Neurotransmitters; Drug; Drosophila; C. elegans;

    Abstract : Mass spectrometry (MS) is one of the most universal analytical techniques due to its label-free detection principle and high chemical specificity, high selectivity, and sensitivity. MS is diverse with many different types of systems to meet different analytical demands from various research areas. READ MORE

  5. 3. ADHD in substance use disorders : prevalence and pharmacotherapy

    Author : Maija Konstenius; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Substance use disorders (SUD) and Attention deficit /hyperactivity disorder (ADHD) are persistent and prevailing disorders that conjointly are associated with negative lifeevents and mental distress. The overall aim of this thesis was to examine the rate of ADHD in substance using populations and to investigate the feasibility and efficacy of methylphenidate pharmacotherapy for treatment of co-existing ADHD and SUD. READ MORE

  6. 4. Static and Dynamic Measurements of Neurotransmitters in Drosophila Brain

    Author : Carina Berglund; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Neurotransmitters, the substances neurons use for communication, and their precursors and metabolites are of obvious importance for the wellbeing of the individual and when the neurotransmitter balance is off it can lead to catastrophic suffering as in the addiction to drugs or in neurodegenerative diseases. By understanding how neurons communicate with the environment, treatment may be found to aid in the symptoms of unbalance. READ MORE

  7. 5. When ADHD and substance use disorders coexist : etiology and pharmacological treatment

    Author : Charlotte Skoglund; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Individuals with attention-deficit hyperactivity disorder (ADHD) and comorbid substance use disorder (SUD) comprise a significant group of patients displaying various degrees of personal suffering, entailing a substantial economical burden on society and presenting with challenges in treatment. The overlap between the two disorders is well established, but the underlying genetic and environmental mechanisms of their coexistence, are poorly understood. READ MORE