Search for dissertations about: "mevalonate kinase"

Found 4 swedish dissertations containing the words mevalonate kinase.

  2. 1. Studies on the regulatory roles of cholesterol and bile acids

    Author : Charlotte Murphy; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cholesterol; cholic acid; bile acids; cholesterol homeostasis; squalene epoxidase; mevalonate kinase; cob I alamin adenotransferase; SREBP; NF-Y;

    Abstract : Cholesterol is essential for normal growth and development in mammals. However, excess cholesterol can be harmful leading to diseases such as atherosclerosis and gallstones. Once formed the ring structure of cholesterol cannot be catabolised by the body and must therefore be converted to other compounds for excretion. READ MORE

  4. 2. Signaling mechanisms in Streptococcal M1 proteininduced inflammation and injury in the lung

    Author : Songen Zhang; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Streptococcus pyogenes of the M1 serotype is frequently associated with severe streptococcal infections. Acute lung injury is recognized as a key component in the pathophysiology of streptococcal M1 proteininduced inflammation. READ MORE

  5. 3. Cell-matrix interactions : master regulators of cancer cell fate?

    Author : Sara Göransson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The development and homeostasis of a multicellular organism require fundamental biological processes like cell proliferation, cell differentiation, cell migration, and controlled cell death. The extracellular matrix (ECM) guides many of these functions, via cell-matrix interactions that function as mechanical and biochemical signaling hubs. READ MORE

  6. 4. Initiation of Protein Biosynthesis in Skeletal Muscles at Feeding

    Author : Britt-Marie Iresjö; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Protein synthesis; Translation initiation; amino acids; Snat 2; MHC2A; IGF-I;

    Abstract : Background and aim. Artificial nutrition by intravenous feeding has for decades indicated less than optimal support of whole-body protein metabolism and balance during some treatment conditions. READ MORE